Product Profile Product Name TMEM119 Rabbit Polyclonal Antibody Antibody Type Primary Antibodies Immunogen Synthetic peptide within human TMEM119 aa 11-52 / 283. Key Feature Clonality Polyclonal Isotype IgG Host Species Rabbit Tested Applications FC ICC/IF WB WB:1:5000IF:1:50-1:100FC:1:100-1:500 Species Reactivity Human Mouse Concentration 1mg/ml Purification Affinity purified Target Information Gene Symbol TMEM119 Gene Synonyms OBIF Molecular Weight(MW) 29KD Function Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation. Cellular Localization Endoplasmic reticulum membrane, Cell membrane, Cytoplasm. Database Links Protein Accession Q4V9L6 Application Application Notes WB:1:5000 IF:1:50-1:100 FC:1:100-1:500 Additional Information Form Liquid Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. Storage Buffer 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide. Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
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