Tongkat Ali 200:1 Extract is classified as a phytoandrogen plant due to its pharmacological effect on hormones. In general, the best Tongkat Ali Exacts are hot water extracted, of Malaysian origin, and are standardized for 1.5%-3% Eurycomanone and 20-22% Eurypeptides.These high-quality Tongkat Ali Extracts have been studied for over 20 years and have proven to increase testosterone, boost luteinizing hormone, reduce cortisol, and increase the release rate of free testosterone from SHBG. Tongkat Ali Extract does this by not only boosting testosterone through the traditional hypothalamic-pituitary-gonadal axis but also a secondary pathway by activating the hypothalamic-pituitary-adrenal axis. This indicates that testosterone levels will rise higher with regular Tongkat Ali use than they would through substances that only affect the hypothalamic-pituitary-gonadal-axis. A recent 2021 study showed that Tongkat Ali demonstrates steroidogenic effects on young men. Results showing an increase in free testosterone levels may be due to greater hormone production via the previously mentioned hypothalamic-pituitary-adrenal axis.Studies have shown that Tongkat Ali can boost testosterone levels in men by up to 37% over a 12-week period. In one study, participants received Tongkat Ali extract every day for 8 weeks. After just 4 weeks, the average increase in free testosterone was 28%.Another study, which gave participants 400 mg of Tongkat Ali daily, found that the treatment resulted in significant increases in total and free testosterone levels. The supplement even increased muscle mass, strength, and recovery.Tongkat Ali is a natural source of compounds known as quassinoids. These compounds release luteinizing hormone, which assists the body in producing greater levels of testosterone. The herb also increases the release rate of free testosterone from the binding hormone sex-hormone-binding-globulin (SHBG). The herb also helps to raise testosterone levels by reducing cortisol. Cortisol, also known as the stress hormone, is a testosterone killer. When the body is stressed, it produces less testosterone. So, when cortisol levels are reduced, testosterone levels naturally increase. A recent meta study that looked at 150 papers on Tongkat Ali found that the findings of human clinical studies revealed a promising efficacy of Tongkat Ali to treat erectile dysfunction in sexually sluggish males by improving penile erection, erectile hardness, and sexual performance. The clinical significance of Tongkat Ali in male infertility was also evidenced by significantly improving semen volume, concentration of sperms, and proportion of sperms having normal morphology, sperm motility, sexual libido, and overall sexual satisfaction.
