Specification Full name TTC38 rabbit polyclonal antibody Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background TTC38 (tetratricopeptide repeat domain 38) is a 469 amino acid protein that contains three TPR repeats and belongs to the TTC38 family. The gene that encodes TTC38 consists of over 26,000 bases and maps to 22q13. Housing over 500 genes, chromosome 22 is the second smallest chromosome in the human genome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. In addition, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. Swissprot No Q5R3I4 Gene Accession BC018918 WB Predicted band size 53 kDa WB Positive control / WB Recommended dilution 1000-5000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human tonsil IHC Recommended dilution Recommended dilution: 50-300 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P112483-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or TTC38 antigen-treated (Neutralization experiment) using P112483(TTC38 Antibody) at dilution 1/85
