Uric Acid for Interference Testing

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Uric Acid for Interference Testing Catalog number: B2010199 Lot number: Batch Dependent Expiration Date: Batch dependent Volume/Weight: 1 mL at 20 mg/mL pH: na Supplied as: Ready-t o-use Appearance: Solution Applications: highly concentrated solution of Uric Acid (20 mg/mL) provided with the corresponding diluent. Solution can be spiked in specimen to test Uric Acid interference in various assays. Storage: -20C Keywords: 2,6,8-Trihydroxypurine Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um. Uric Acid for Interference Testing is a biotechnology-grade reagent formulated to simulate endogenous uric acid interference in clinical assay validation workflows. Supplied as a highly concentrated 20 mg/mL solution, this ready-to-use reagent enables researchers to spike specimens and evaluate assay robustness, specificity, and analytical accuracy. It is particularly useful in validating enzymatic assays, immunoassays, and biochemical platforms where uric acid may impact signal detection or assay kinetics due to its redox activity and potential cross-reactivity. Researchers in nephrology, metabolic profiling, and diagnostic assay development rely on interference testing to meet CLSI EP07 guidelines and ensure reliable performance across diverse patient samples. This reagent is manufactured using ultrapure water and filtered through 0.22 µm membranes to ensure minimal background interference and maximum reproducibility. Supplied in a 1 mL format and stored at –20°C, it integrates seamlessly into manual and automated workflows. Whether you're developing a uric acid-sensitive assay or troubleshooting unexpected signal variation, this reagent provides a precise and reproducible solution for interference evaluation. Key benefits: 20 mg/mL uric acid solution for interference simulation in clinical assays Supports EP07-compliant assay validation and robustness testing Ready-to-use format with corresponding diluent included Filtered through 0.22 µm membranes using ultrapure water Stored at –20°C for long-term stability and reproducibility Products are for in vitro research use only (RUO). References 1: Giordano C, Karasik O, King-Morris K, Asmar A. Uric_Acid as a Marker ofKidney Disease: Review of the Current Literature. Dis Markers. 2015;2015:382918. 2: Arakawa H, Amezawa N, Katsuyama T, Nakanishi T, Tamai I. Uric_acid analogueas a possible xenobiotic marker of uric_acid transporter Urat1 in rats. DrugMetab Pharmacokinet. 2019 Apr;34(2):155-158. 3: Kaya SI, Kurbanoglu S, Ozkan SA. Nanomaterials-Based Nanosensors for theSimultaneous Electrochemical Determination of Biologically Important Compounds:Ascorbic Acid, Uric_Acid, and Dopamine. Crit Rev Anal Chem. 2019;49(2):101-125. 4: Huang CT, Chen ML, Huang LL, Mao IF. Uric acid and urea in human sweat. ChinJ Physiol. 2002 Sep 30;45(3):109-15. PMID: 12817713. 5: Gong CB, Li ZY, Liu LT, Wei YB, Yang X, Chow CF, Tang Q. Photocontrolledextraction of uric_acid from biological samples based on photoresponsive surfacemolecularly imprinted polymer microspheres. J Sep Sci. 2017 Mar;40(6):1396-1402. 6: Wu X, Zhang J, Liu T, Yan M, Liu H, Xie H, Zhang S, Sun B, Ke B, Zhou H. Uric_acid crystal could inhibit Numb-induced URAT1 lysosome degradation in uric acidnephropathy. J Physiol Biochem. 2015 Jun;71(2):217-26. 7: Li L, Wang J, Chen Z. Colorimetric determination of uric_acid based on thesuppression of oxidative etching of silver nanoparticles by chloroauric acid.Mikrochim Acta. 2019 Dec 5;187(1):18. All Interference Products Brochure Show more