D mannose, cranberry and green tea extract for urinary tract and bladder health A three ingredient formula for ongoing daily use. Each capsule provides 243mg D mannose, 146mg green tea extract (45% EGCG) and 99mg cranberry extract. D mannose is a simple sugar that is poorly metabolised in humans and is largely excreted unchanged in the urine. Research suggests it acts by binding to the type 1 fimbriae, the adhesion structures on E. coli, so that the bacteria are less able to attach to the bladder wall and are carried out with urine instead. E. coli is the organism behind most urinary infections.Cranberry has traditionally been used for urinary health. Research suggests its proanthocyanidins act by a similar anti adhesion route, distinct from D mannose (Liu et al, 2008). Green tea contains EGCG and EGC, both of which have shown anti microbial activity against E. coli, and EGC has been shown to be excreted in urine at a concentration high enough to be relevant (Reygaert and Jusufi, 2013). The vegetarian capsule shell makes this suitable for most dietary requirements. Key benefits: D mannose at 243mg per capsule Anti adhesion mechanism supported in research Cranberry and green tea alongside Each capsule contains: %NRV* D-Mannose 243 mg † Green Tea Extract (45% EGCG) 146 mg † Cranberry Extract 99 mg † † Nutrient Reference Value (NRV*) not established D-Mannose, Hydroxypropyl Methylcellulose (capsule), Green Tea Extract, Cranberry Extract. Directions for use:Recommended dose 3 capsules per day.This provides 729mg D mannose, 438mg green tea extract and 297mg cranberry extract daily. The recommended dose can be changed as directed by your healthcare practitioner. Do not exceed the recommended dose.Drinking plenty of water through the day supports regular urination, and D mannose relies on the bladder being emptied regularly. If you have symptoms of a urinary infection, see your GP rather than managing it yourself with a supplement, because an untreated infection can worsen. If pregnant or breastfeeding, consult your healthcare practitioner before use. This product should not be used as a substitute for a varied diet.