Ortho Molecular UT Defense Immune Health UT Defense is a formula designed to support kidney and urinary tract health and to help to promote microbial balance. UT Defense is designed to support kidney and urinary tract health and to help to promote healthy microbial balance. The formula includes Anthocran®, a cranberry extract standardized to 36 mg proanthocyanidins (PACs), which has been shown to be the optimal daily dose for urinary tract health. UT Defense also includes dandelion leaf extract to naturally flush out urinary passages and Ellirose™, an extract of hibiscus flower shown to promote healthy microbial balance in the urinary tract. Each capsule of UT Defense includes 120 mg Anthocran®, 225 mg dandelion leaf extract and 200 mg Ellirose™. The urinary tract is made up of the kidneys, bladder, and the tubes leading to and from these organs, the ureters and the urethra, and is responsible for producing urine and eliminating it from the body. As an important organ of elimination, a healthy urinary system is essential to the health of the entire body. Many individuals, including pregnant women and the elderly, may benefit from additional support for the urinary tract. UT Defense offers a full spectrum of kidney and urinary tract support, promoting microbial balance, healthy detoxification, and urine excretion. Key Benefits and Features: Provides Support for Healthy Urinary Tract Function Supports Healthy Microbial Balance in the Urinary Tract Helps Maintain a Healthy Mucosal Surface in the Urinary Tract Promotes Healthy Immune Function Ingredients Serving Size: 1 Capsule Amount/Serving Dandelion Leaf Extract 225 mg Hibiscus Flower Extract (Ellirose) 200 mg Cranberry Fruit Extract (Anthocran) (Standardized to contain 36 mg Proanthocyanidins) 120 mg Other Ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, and Silicon Dioxide. Does Not Contain: Gluten, corn, yeast, artificial colors, or flavors. Suggested Use Take 1 capsule per day, or as recommended by your health care professional. Warning: If you are pregnant or nursing, consult your physician before taking this product. Keep out of the reach of children. Storage: Keep tightly closed in a cool, dry place. More Info. Cranberries/Anthocran® Cranberry juice has been used historically as a remedy for urinary tract health. The mechanism of action of cranberry juice and its extracts is the inhibition of microbial binding to host cell surface membranes. In vitro studies have observed it to promote healthy microbial balance facilitated by proanthocyanidins PACs), which impact bacterial adherence and maintain the microbial health of the urinary tract. A recent meta-analysis of 10 clinical trials and 1,494 subjects showed supplementation of cranberry-containing products supported urinary tract health and urine flow in women and children, showing greater benefit for cranberry users by 38%. A meta-analysis of the results of four randomized controlled clinical trials found that prophylactic use of cranberries significantly supported urinary tract health over a 12-month period, compared with placebo. In a 2015 clinical trial comparing the use of Anthocran® plus lifestyle intervention to only lifestyle intervention, there was shown to be a 73.3% reduction in the frequency of urinary tract challenges in the Anthocran® group compared to the lifestyle control group, which saw a 15.4% decrease. In addition, 31.8% of the Anthocran® subjects were symptom-free, and none of the control group were symptom-free. It was also noted that there was a decrease in any urinary challenge duration from those who only received lifestyle intervention. Hibiscus sabdariffa H. sabdariffa extracts have long been used in herbal teas and for urinary tract support. H. sabdariffa calyx in a 10:1 extract (Ellirose™ extract) includes compounds that promote microbial balance and prevent bacteria from adhering to the bladder wall, including substantial amounts of flavonoids, sambubiocides, anthocyanidins, proanthocyanidins, and chlorogenic acids. In addition, other ingredients such as polysaccharides and a high concentration of simple organic acids provide urinary tract support. An in vitro study on Hibiscus calyx and protocatechuic acid has shown its ability to promote microbial balance, mediated by protocatechuic acid content and a six-month, double-blind, placebo controlled study, found 200 mg of H. sabdariffa extract taken once a day, significantly promoted urinary tract health by 77%.
