THIS IS THE SOLUTION ONLY Potential Benefits of an Ozonated Vaginal Irrigation & Lavage Solution Ozonated solutions (ozonated glycerin in a saline solution) are used in some veterinary settings for their oxidative antimicrobial and biofilm-disrupting properties. When applied as a vaginal irrigation or lavage in mares, proposed benefits include: 1. Broad-Spectrum Antimicrobial Activity Ozone has demonstrated in vitro activity against: Gram-positive and Gram-negative bacteria Fungi and yeast Some viruses Its mechanism involves oxidative disruption of microbial cell membranes and intracellular components. 2. Biofilm Disruption Ozone may help break down microbial biofilms, which can contribute to: Chronic vaginitis Persistent contamination Reduced response to conventional antimicrobial therapy 3. Reduction of Vaginal Microbial Load Pre-breeding vaginal cleansing may: Reduce ascending contamination risk during breeding or AI Support improved uterine health in mares predisposed to post-breeding endometritis 4. Anti-Inflammatory & Oxygenation Effects (Proposed) Literature documents that ozone may: Modulate local inflammatory responses Improve tissue oxygen metabolism Promote mucosal healing Evidence for these effects in equine reproductive tissue is still evolving. 5. Non-Antibiotic Approach Because ozone acts via oxidative mechanisms: There is no known microbial resistance pattern It may be used as an adjunct to reduce reliance on antibiotics in selected cases Important Considerations Clinical evidence in equine reproduction remains limited compared to conventional therapies. Not a substitute for proper diagnostic evaluation (culture, cytology, ultrasound). Should be used under veterinary supervision.
