Wheaton 4000 mL Double Sidearm Spinner Flask – Borosilicate Glass, Mixed Arm Configuration The Wheaton 4000 mL Spinner Flask is a high-capacity, precision-engineered vessel designed for large-scale cell culture and fermentation. Manufactured from Type I, Class A borosilicate glass, this flask offers exceptional thermal resistance and optical clarity for monitoring delicate cell monolayers or suspension cultures. This specific model features a double sidearm configuration, including one threaded arm and one unthreaded arm, providing a hybrid interface for both airtight sensor integration and traditional venting. Designed for use on a magnetic stir plate, the internal impeller system ensures uniform nutrient distribution and optimal gas exchange, making it a critical tool for scaling up biological production. Technical Performance and Design Borosilicate Glass Construction: Fabricated from low-extractable borosilicate glass that meets USP Type I standards, ensuring chemical purity and the ability to withstand repeated high-temperature autoclave cycles. Hybrid Sidearm Interface: Features one threaded sidearm for secure attachment of probes or gas lines and one unthreaded arm for standard venting, offering maximum flexibility for diverse experimental setups. Threaded Center Neck: The large center neck is designed to accommodate a threaded headcap and impeller assembly, providing a robust, airtight seal that maintains a sterile environment during long-term incubation. Optimal Mixing Dynamics: The flask geometry is engineered to work with Wheaton impeller systems to provide gentle, low-shear agitation, which is essential for protecting sensitive cell lines from mechanical stress. Product Specifications Brand/Manufacturer: Wheaton (DWK Life Sciences) Capacity: 4000 mL (4 Liters) Material: Borosilicate Glass (USP Type I) Sidearm Configuration: Double (1 Threaded / 1 Unthreaded) Center Neck Style: Threaded Autoclavable: Yes (All components) Compatibility: Standard 4L Wheaton impeller and cap assemblies. Key Benefits & Applications Bioprocess Development: Ideal for scaling up from small Erlenmeyer flasks to pilot-scale production for vaccines, recombinant proteins, and monoclonal antibodies. Anchorage-Dependent Culture: When used with microcarriers, this flask provides the high surface-to-volume ratio required for the expansion of adherent cells. Reduced Contamination Risk: The threaded headcap and sidearm fittings allow for a highly controlled, closed-system environment compared to traditional plug-style flasks. Longevity and Reusability: The heavy-wall glass construction is designed for years of service, providing a sustainable and cost-effective alternative to single-use bioreactor bags. All product names, logos, and brands are property of their respective owners.
