dTTP, namely 2'-Deoxythymidine-5'-triphosphate, is used for molecular biological reactions, such as PCR, real-time PCR, RT-PCR, cDNA Synthesis, primer extension reaction, DNA sequencing, DNA labeling etc. This product was in the form of sodium solution, prepared with ultrapure water, adjust pH 7.0 with a high purity NaOH solution. The concentration of dTTP is 100 mmol/L. Ultra-high purity dTTP: >99% trisphosphate by HPLC; Free of DNase and RNase contamination. Features Greater than 99% purity confirmed by HPLC Free of human and E.coli DNA Highly stable Applications Long-range PCR (20 kb) cDNA synthesis and RT-PCR Real-time PCR Standard PCR High fidelity PCR Specifications Concentration 100 mM CAS NO. 18423-43-3 Form Liquid Purity >99% Label or Dye Unlabeled For Use With (Application) PCR Amplification Components Components No. Name 10120ES74 10120ES80 10120ES96 10120ES97 10120 dTTP Solution (100 mmol/L) 400 μL 1 mL 25 mL 400 mL Shipping and Storage The product is shipped with dry ice and can be stored at -15℃ ~ -25℃ for 2 years. Please avoid repeated freeze-thaw. Documents: Safety Data Sheet 10120_MSDS_HB220429 Manuals 10120_Manual_HB20260625 Citations & References: [1] Zhang J, Zhang G, Zhang W, et al. Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer [published online ahead of print, 2022 May 10]. Cell Death Differ. 2022;10.1038/s41418-022-01012-0. doi:10.1038/s41418-022-01012-0(IF:15.828) [2] Chai Q, Wang X, Qiang L, et al. A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy. Nat Commun. 2019;10(1):1973. Published 2019 Apr 29. doi:10.1038/s41467-019-09955-8(IF:11.878) [3] Wang X, Ni J, You Y, et al. SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade. EMBO J. 2021;40(24):e108080. doi:10.15252/embj.2021108080(IF:11.598) [4] Feng Y, Wang Y, Wang X, et al. Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription. Genome Biol. 2020;21(1):296. Published 2020 Dec 8. doi:10.1186/s13059-020-02201-1(IF:10.806) [5] Tao X, Wan X, Wu D, Song E, Song Y. A tandem activation of NLRP3 inflammasome induced by copper oxide nanoparticles and dissolved copper ion in J774A.1 macrophage. J Hazard Mater. 2021;411:125134. doi:10.1016/j.jhazmat.2021.125134(IF:10.588) [6] Alolga RN, Opoku-Damoah Y, Alagpulinsa DA, et al. Metabolomic and transcriptomic analyses of the anti-rheumatoid arthritis potential of xylopic acid in a bioinspired lipoprotein nanoformulation. Biomaterials. 2021;268:120482. doi:10.1016/j.biomaterials.2020.120482(IF:10.317) [7] Mo X, Du S, Chen X, et al. Lactate Induces Production of the tRNAHis Half to Promote B-lymphoblastic Cell Proliferation. Mol Ther. 2020;28(11):2442-2457. doi:10.1016/j.ymthe.2020.09.010(IF:8.986) [8] Hao W, Han J, Chu Y, et al. Lower fluidity of supported lipid bilayers promotes neuronal differentiation of neural stem cells by enhancing focal adhesion formation. Biomaterials. 2018;161:106-116. doi:10.1016/j.biomaterials.2018.01.034(IF:8.806) [9] Lin Z, Xia S, Liang Y, et al. LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription. Theranostics. 2020;10(19):8834-8850. Published 2020 Jul 11. doi:10.7150/thno.45158(IF:8.579) [10] Liu H, Xing R, Ou Z, et al. G-protein-coupled receptor GPR17 inhibits glioma development by increasing polycomb repressive complex 1-mediated ROS production. Cell Death Dis. 2021;12(6):610. Published 2021 Jun 12. doi:10.1038/s41419-021-03897-0(IF:8.469)
