September 15–18, 2026 · 9:00 AM start, all times CEST · Live online This rigorous yet accessible course in pharmacokinetics has trained more than 2,700 pharmaceutical scientists worldwide over nearly four decades. The 2026 European course brings the same content and physics-based methodology to a Central European time zone, taught by Leslie Z. Benet, Ph.D. (Professor Emeritus, UCSF), with lectures led by Dr. Benet and workshops in small groups led by individual tutors. Course Format 7 Benet Live Lectures with Open DiscussionReal-time questions and discussion with Dr. Benet. Lecture slides emailed prior to the course. Recordings of lectures will not be provided, but registrants are free to record the lectures for their own use. 7 Interactive WorkshopsSmall group format led by currently active industrial scientists and academic faculty, all trained in the Benet Lab. Completely new workshop problems. 2 Further Lectures Previously Present in the UCSF CourseExpert presentations on PK/PD Modeling and Macromolecular Pharmacokinetics. Fully Virtual FormatAttend from anywhere. Materials emailed before the course begins. Answer keys distributed after each workshop. Daily curriculum Day 1 (Tuesday, September 15) Renal and hepatic clearance, drug input, bioavailability Day 2 (Wednesday, September 16) Protein binding, MRT concepts, dissolution, half-life, multiple dosing Day 3 (Thursday, September 17) PBPK, saturable kinetics, BCS, BDDCS, ECCS, renal clearance complications Day 4 (Friday, September 18) PK/PD modeling, macromolecular pharmacokinetics, review of basic concepts Detailed schedule (all times CEST) Day 1 — Tuesday, September 15 9:00–9:15 Introduction 9:15–10:30 Lecture 1 (Dr. Benet): Deriving Renal and Hepatic Clearance Following IV Bolus Dosing 10:30–10:45 Break 10:45–12:30 Workshop 1 12:30–1:00 Break 1:00–2:00 Lecture 2 (Dr. Benet): Drug Input, Mean Residence Time, Bioavailability, Volume of Distribution 2:10–3:55 Workshop 2 Day 2 — Wednesday, September 16 9:00–10:00 Lecture 3 (Dr. Benet): Protein Binding, Expanding MRT Concepts, Dissolution 10:00–10:15 Break 10:15–11:45 Workshop 3 11:45–12:15 Break 12:15–1:45 Lecture 4 (Dr. Benet): Half-Life, Multiple Dosing Equations, Accumulation 1:45–2:15 Break 2:15–3:45 Workshop 4 Day 3 — Thursday, September 17 9:00–10:30 Lecture 5 (Dr. Benet): PBPK and Clearance Measures, Saturable Kinetics, BCS, BDDCS & ECCS 10:30–10:45 Break 10:45–12:15 Workshop 5 12:15–12:45 Break 12:45–2:00 Lecture 6 (Dr. Benet): Renal Clearance Complications, Mechanistic Models, The New Findings 2:00–2:15 Break 2:15–3:45 Workshop 6 Day 4 — Friday, September 18 9:00–10:00 PK/PD Modeling Lecture: Dr. James A. Uchizono 10:00–10:15 Break 10:15–11:30 Macromolecular Pharmacokinetics Lecture: Dr. Sara Kenkare-Mitra 11:30–12:00 Break 12:00–1:30 Workshop 7 1:30–1:45 Break 1:45–3:00 Lecture 7 (Dr. Benet): Review of Basic Concepts Tutors for EU 2026Dr. Jasleen K. Sodhi (Director, DMPK & Clinical Pharmacology, Septerna, Inc.) and Dr. Miki Susanto Park (Professor of Pharmaceutical Sciences, University of the Pacific) are confirmed for the EU 2026 course. Additional European tutors, former Benet Group members based in Europe, are being recruited and will be announced before the course begins. See the Tutors page for full bios. Additional Lecturers Dr. James A. Uchizono — Professor and Associate Dean, University of the Pacific. PK/PD Modeling, Day 4. Dr. Sara Kenkare-Mitra — Former Senior Vice President, Drug Development, Genentech. Macromolecular Pharmacokinetics, Day 4. Is This Course Right for You? Perfect For Pharmaceutical scientists with little or no formal training in PK Scientists working in adjacent disciplines who use PK concepts Experienced pharmacokineticists interested in a streamlined and integrated framework Research teams focused on analyzing ADME study data Drug development professionals making dosing decisions What You'll Gain New physics-based methodology for PK analysis without differential equations Practical hands-on workshop experience with completely new problem sets Direct Q&A access with Dr. Benet during lectures Comprehensive answer sheets for all workshop problems All materials and slides delivered prior to the course Insights from leading industry scientists and academics Certificate of completion Why this course is differentThe course uses a physics-based teaching methodology validated across thirteen peer-reviewed Benet Lab publications since 2022. It builds a full working command of pharmacokinetics without requiring you to derive differential equations, and it explains phenomena traditional PK teaching glosses over. What students said about the Spring 2026 course "The Lectures and Workshops served as an excellent resource to help better understand Pharmacokinetics from a beginner's perspective. The examples discussed made the course very engaging even for complex topics. Specifically, reiteration of key points during lectures was a great help in connecting various aspects allowing concepts to be grasped easily." "I really enjoyed the course and workshop. The content was intensive, but the depth of expertise that Prof. Benet and my Workshop tutors brought to the sessions was truly remarkable. Their ability to engage with us and clarify complex concepts within just a few days was marvelous. I gained so many valuable takeaways, and the fundamental knowledge I acquired in this field has been incredibly enriching and inspiring. Thank you very much for such an outstanding learning experience!" "Overall, I feel that I learned enough from the course to better understand (i) the language of PK, (ii) how my DMPK colleagues derive these parameters, and (iii) how these parameters describe a molecule's exposure in vivo and its likelihood to elicit a desired PD effect." "Despite this being pretty fast for me, I deeply appreciated the course and it has given me a better perspective on PK in that I can at least understand and contribute (asking better questions) to clin pharmacology teammates as we navigate the early development world together. Thank you so much for your passion and enthusiasm for teaching PK and challenging the norm! It's been an honor to attend this course." "I want to thank Professor Benet and Dr. Sodhi for an incredible course. Professor Benet is a true architect of pharmacokinetics; it was a profound honor to learn from someone who didn't just study the field but actively defined its boundaries. His ability to connect the historical evolution of PK with innovative concepts, like the application of Kirchhoff's Laws, is a testament to his enduring brilliance. This experience was a highlight of my professional education." Limited to 90 Participants Registration fee: $900 USD First-come, first-served No discounts available Questions? Email [email protected]
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