Corning 1000 ml Polycarbonate Erlenmeyer Flask (431146) The Corning 431146 is a premium 1000 ml Erlenmeyer flask engineered for high-yield suspension cultures, media preparation, and storage. Manufactured from medical-grade, optically clear polycarbonate, this flask provides the superior mechanical strength and shatter-resistance necessary for high-speed orbital shaking. The flask features a wide-mouth design for easy filling and access, complemented by molded-in graduations for accurate volume measurement. Delivered gamma-sterilized and certified non-pyrogenic, the 431146 is equipped with a leak-proof plug-seal cap, ensuring aseptic integrity and preventing evaporation during long-term incubation. This flask is the industry standard for researchers performing protein expression, scale-up studies, and general laboratory liquid handling. Technical Performance and Design High-Clarity Polycarbonate: Offers glass-like transparency for effortless visual monitoring of cell growth, turbidity, and contamination, with the added safety of a shatter-proof polymer construction. Optimized for Shaker Applications: The Erlenmeyer geometry and robust wall thickness are designed to withstand the physical stresses of orbital shaking, providing optimal aeration and mixing for suspension cells. Secure Plug-Seal Cap: The high-density polyethylene (HDPE) cap features a deep-skirted plug seal that provides a primary liquid-tight barrier, protecting cultures from external contaminants and preventing leakage. Certified Purity: Each flask is sterilized by gamma irradiation to a Sterility Assurance Level (SAL) of 10^-6 and is certified to be non-pyrogenic and non-cytotoxic. Product Specifications Catalog Number: 431146 Capacity: 1000 ml Material: Polycarbonate (PC) Cap Material: High-Density Polyethylene (HDPE) Cap Style: 43 mm Plug Seal Cap (Solid) Sterility: Sterile (Gamma Irradiated) Graduations: Molded-in increments for quick volume estimation. Packaging: Individually wrapped (Case of 25). Key Benefits & Applications Suspension Cell Culture: The preferred vessel for culturing mammalian, insect, and microbial cells in shakers and incubators. Media & Buffer Storage: Excellent for the sterile preparation and short-to-medium term storage of aqueous reagents and cell culture media. Scale-Up Studies: Provides a reliable platform for transitioning from small-scale plates or tubes to larger production volumes. Single-Use Efficiency: Eliminates the labor and validation costs associated with cleaning and autoclaving traditional glass Erlenmeyer flasks. All product names, logos, and brands are property of their respective owners.