Corning 431147 Erlenmeyer Flask – 1000 mL, Plain Bottom, Vent Cap, Individually Sealed The Corning 431147 is a 1L (1000 mL) high-capacity Erlenmeyer flask designed for large-scale cell culture expansion and laboratory-scale production. Featuring a plain (flat) bottom design, this flask is optimized for the cultivation of suspension cell lines that require uniform mixing and low shear stress. Manufactured from optically clear, shatterproof polycarbonate, the 431147 provides a robust and safe alternative to traditional glass vessels for use in orbital shakers and incubators. Each flask is supplied individually wrapped and gamma-sterilized, ensuring the highest level of aseptic integrity for critical biopharmaceutical research and diagnostic manufacturing. Technical Performance and Design 1000 mL Large-Volume Capacity: Provides the necessary volume for significant biomass expansion, serving as a critical bridge between laboratory-scale R&D and pilot-scale bioreactor inoculation. Plain (Flat) Bottom Design: Engineered for smooth fluid dynamics at various shaking speeds, ensuring consistent nutrient distribution for mammalian and insect cell cultures. 0.2 µm Hydrophobic Vent Cap: The breathable polypropylene cap features an integrated high-efficiency membrane that facilitates sterile gas exchange (O2 and CO2) while preventing microbial contamination. Individually Wrapped: Each flask is sealed in its own protective packaging to maintain sterility and prevent surface contamination, making it ideal for use in strictly regulated cleanroom environments. Product Specifications Catalog Number: 431147 Capacity: 1000 mL Bottom Style: Plain / Flat Bottom Neck Style: Wide Mouth Material: Polycarbonate (USP Class VI) Cap Type: Vent Cap (0.2 µm Membrane) Sterility: Sterile (Gamma Irradiated, SAL 10⁻⁶) Key Benefits & Applications Bioprocess Scale-up: A staple in the expansion of CHO, HEK293, and Sf9 cell lines, providing the surface-to-volume ratio required for healthy culture growth. Sterile Media Storage: The 1L capacity and secure vent cap make this vessel excellent for storing, transporting, and warming large volumes of sterile media or buffers. Laboratory Safety: The polycarbonate construction is virtually unbreakable, eliminating the risks of glass fragments and sample loss in high-speed orbital shakers. Cleanroom Compatibility: The individual sealing ensures that the exterior of the flask remains sterile until it is brought into the sterile field, simplifying transfer protocols. All product names, logos, and brands are property of their respective owners.
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