Interleukin-4 (IL-4) is a cytokine that belongs to the interleukin family. Interleukin 4 is mainly produced by T cells, B cells, macrophages and other immune cells.IL4 is a key regulatory molecule that plays an important role in the Th2 type of immune response. Interleukin 4 has a variety of biological functions that promote B cell class switching to IgE and IgG1, thereby enhancing the effects of humoral immunity. In addition, IL4 inhibits the activation of macrophages and dendritic cells and suppresses their release of inflammatory cytokines. In clinical practice, interleukin 4 is widely used in the treatment of allergic diseases, such as asthma and allergic rhinitis. This product is available as Fluids, high activity, high purity, low endotoxin, NO labeling. Product Properties Synonyms Mouse B cell growth factor 1; BCDF; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; IL4; IL-4; IL-4B_cell stimulatory factor 1; IL4E12; interleukin 4; interleukin-4; Species Mouse Source HEK293 Ceslls Sequence His21-Ser140 Accession P07750 Tag NO Predicted molecularmass 13.6 KDa Endotoxin 95%, determined by SDS-PAGE Activity Measured in a cell proliferation assay using HT2 mouse T cells. The ED50 for this effect is 0.3-1.5 ng/mL Formulation Dissolved in sterile PBS buffer. Appearance Fluids Shipping and Storage -85~-65℃ storage, valid for 1 year after receipt. Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃. Figure Figure 1.Measured in a cell proliferation assay using HT-2 mouse T cells. The EC50 for this effect is 0.2-1.0 ng/mL. Figure 2.4 ug/lane protein was resolved with SDS-PAGE under non-reducing (NR) and reducing (R) conditions and visualized by Coomassie Blue staining. Cautions 1. For your safety and health, please wear lab coat and disposable gloves. 2. This product is for scientific research purposes only.
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