Product Properties Alternative Names FcRn alpha chain, FCGRT, FCRN, FCGRT&B2M Species Cynomolgus,Rhesus macaque Expression Sequence Ala24-Ser297(FCGRT) and Ile21-Met119(B2M) Accession Q8SPV9&Q8SPW0 Tag C-His-Avi Expression System HEK293 Molecular Weight The protein has a predicted MW of 46.5 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on SDS-PAGE result. Purity > 95% as determined by SDS-PAGE and HPLC. Endotoxin < 1.0 EU per μg by the LAL method. Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. Appearance Lyophilized Powder Biological Activity 【SPR Data】Biotinylated Cynomolgus/Rhesus macaque FcRn, His Tag captured on CM5 Chip via Anti-His Antibody can bind Rituximab, hFc Tag with an affinity constant of 0.48 μM as determined in SPR assay . Reconstitution Method Before opening, centrifuge briefly. Reconstitute the lyophilized protein with distilled water to a concentration exceeding 100 μg/mL. Aliquot after initial reconstitution to avoid repeated freeze-thaw cycles. Features High purity, high activity, low endotoxin, high batch-to-batch consistency Storage Store at -25 to -15°C. Once received, the product is valid for one year. After reconstitution, store under sterile conditions at -85 to -65°C. The product is valid for three months.
