Transmembrane protein 27 (TMEM27/collectrin), a glycoprotein and homolog of angiotensin-converting enzyme 2 (ACE2), is a regulator of renal amino acid uptake in the proximal tubule and may have a protective role in hypertension. Mature human Collectrin consists of a 127 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 60 aa cytoplasmic domain. Collectrin is highly expressed in the proximal convoluted tubules of the renal collector and inhibits the proliferation of tubular epithelial cells. Product Information Product Information. Catalog Number Size Recombinant Human Collectrin/TMEM27 Protein,hFc Tag 96591ES60 100 μg 96591ES76 500 μg Product Properties Synonyms NX-17 Protein,Human,NX17 Protein,Human Species Human Expression Sequence Glu15-Pro141,with C-hIgG1 Fc Accession Q9HBJ8 Tag C-hFc Tag Expression System HEK293 Molecular Weight 53-60 kDa (Reducing) Purity > 95% as determined by SDS-PAGE. Endotoxin < 0.1 EU/μg Formulation PBS, pH7.4. Appearance Lyophilized Powder Reconstitution Method Reconstitute at 0.1-1 mg/mL according to the size in ultrapure water after rapid centrifugation. Product Features High activity, high purity, low endotoxin, high lot-to-lot consistency Storage Store at -25 ~ -15°C, valid for 1 year after receipt. After reconstitution, store at 2~8°C under sterile conditions, valid for 7 days. After reconstitution, store at -85 ~ -65°C under sterile conditions, valid for 3 months. Documents: Manuals 96591_Manual_HB20260421
