Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is an inhibitory receptor belonging to the CD28 immunoglobulin subfamily, expressed primarily by T-cells . The family includes CD28, CTLA-4 and ICOS as well as other proteins including PD-1, BTLA and TIGIT .Its ligands, CD80 and CD86, are typically found on the surface of antigen-presenting cells and can either bind CD28 or CTLA-4, resulting in a costimulatory or a co-inhibitory response, respectively. Specifications Cat.No. 96595ES60 / 96595ES76 Size 100 μg / 500 μg Components Name 96595ES60 96595ES76 Recombinant Rat CTLA-4/CD152 Protein,hFc Tag 100 μg 500 μg Performance parameters Synonyms Celiac Disease 3,CD152,CTLA4,CTLA-4 Species Rat Expression Sequence: Ile38-Asp161,with C-terminal Fc Accession Q62859 Tag C-hFc Tag Expression System HEK293 Molecular Weight 45-55 kDa (Reducing) Purity > 95% as determined by SDS-PAGE. Endotoxin
