Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and it is also found in regulatory T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. Product Information Product Information. Catalog Number Size Recombinant Rat CTLA-4/CD152 Protein,His Tag 96596ES60 100 μg 96596ES76 500 μg Product Properties Synonyms CTLA4,CD152 Species Rat Expression Sequence Ile38-Asp161,with C-terminal His Accession Q62859 Tag C-His Tag Expression System HEK293 Molecular Weight 19-26 kDa (Reducing) Purity > 95% as determined by SDS-PAGE. Endotoxin < 0.1 EU/μg Formulation PBS, pH7.4. Appearance Lyophilized Powder Reconstitution Method Reconstitute at 0.1-1 mg/mL according to the size in ultrapure water after rapid centrifugation. Product Features High activity, high purity, low endotoxin, high lot-to-lot consistency Application Example ELISA Data: Immobilized CTLA-4/CD152 His Tag Protein, Rat at 2.0 μg/mL (100 μL/well) can bind B7-1/CD80 Fc Chimera Protein, Mouse with EC50 of 1.36-1.57 ng/mL. Storage Store at -25 ~ -15°C, valid for 1 year after receipt. After reconstitution, store at 2~8°C under sterile conditions, valid for 7 days. After reconstitution, store at -85 ~ -65°C under sterile conditions, valid for 3 months. Documents: Manuals 96596_Manual_HB20260421
