Alpha-Cyclodextrin Solution 5% (w/v) Catalog # K1010005A Lot # Batch Dependent Expiration Batch Dependent Amount 25 mL Concentration 5% (w/v) Supplied as Solution Applications Solubility enhancement, molecular assemblies, organic synthesis Storage 2–8°C Keywords α-Schardinger dextrin, Cyclomaltohexaose, α-Cyclodextrin, Cyclohexaamylose Grade Biotechnology grade; ultrapure water, 0.22 µm filtered This 5% (w/v) solution of alpha-cyclodextrin (α-CD) is a high-purity reagent used in host–guest chemistry, solubility enhancement, and supramolecular assemblies. α-CD is a cyclic oligosaccharide composed of six glucose units, forming a hydrophobic cavity that can encapsulate small organic molecules. Its smaller cavity size compared to β- and γ-cyclodextrins makes it ideal for selective complexation of low-molecular-weight guests. Formulated in ultrapure water and filtered through 0.22 µm membranes, this biotechnology-grade solution is supplied in 25 mL aliquots and stored at 2–8°C. α-CD is widely used in pharmaceutical formulation, food science, and polymer chemistry. It has demonstrated utility in cholesterol modulation, antimicrobial delivery, and hydrogel formation. Its safety profile and functional versatility make it suitable for both analytical and preparative workflows. Key benefits: 5% (w/v) α-CD solution for selective molecular encapsulation Supports host–guest chemistry, solubility enhancement, and hydrogel design Filtered through 0.22 µm for analytical reproducibility Packaged in ultrapure water; biotechnology grade Compatible with pharmaceutical, biochemical, and food science workflows Indication for Use:This product is for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use. References:1: Domiński A, Konieczny T, Kurcok P. α-Cyclodextrin-Based Polypseudorotaxane Hydrogels. Materials (Basel). 2019 Dec 28;13(1):133. 2: Liu L, Feng X, Pei Y, Wang J, Ding J, Chen L. α-Cyclodextrin concentration-controlled thermo-sensitive supramolecular hydrogels. Mater Sci Eng C Mater Biol Appl. 2018 Jan 1;82:25-28. 3: Henck JMM, Bis-Souza CV, Pollonio MAR, Lorenzo JM, Barretto ACS. Alpha-cyclodextrin as a new functional ingredient in low-fat chicken frankfurter. Br Poult Sci. 2019 Dec;60(6):716-723. 4: Pilely K, Bakke SS, Palarasah Y, Skjoedt MO, Bartels ED, Espevik T, Garred P. Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis. Atherosclerosis. 2019 Apr;283:35-42. 5: Femminò S, Penna C, Bessone F, Caldera F, Dhakar N, Cau D, Pagliaro P, Cavalli R, Trotta F. α-Cyclodextrin and α-Cyclodextrin Polymers as Oxygen Nanocarriers to Limit Hypoxia/Reoxygenation Injury: Implications from an In Vitro Model. Polymers (Basel). 2018 Feb 22;10(2):211. 6: Bessell E, Fuller NR, Markovic TP, Lau NS, Burk J, Hendy C, Picone T, Li A, Caterson ID. Effects of α-Cyclodextrin on Cholesterol Control and Hydrolyzed Ginseng Extract on Glycemic Control in People With Prediabetes: A Randomized Clinical Trial. JAMA Netw Open. 2020 Nov 2;3(11):e2023491. 7: Aroob I, Ahmad N, Aslam M, Shaeer A, Rashid N. A highly active α-cyclodextrin preferring cyclomaltodextrinase from Geobacillus thermopakistaniensis. Carbohydr Res. 2019 Jul 15;481:1-8. 8: Romeo L, Lanza Cariccio V, Iori R, Rollin P, Bramanti P, Mazzon E. The α-Cyclodextrin/Moringin Complex: A New Promising Antimicrobial Agent against Staphylococcus aureus. Molecules. 2018 Aug 21;23(9):2097. 9: EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Silano V, Barat Baviera JM, Bolognesi C, Cocconcelli PS, Crebelli R, Gott DM, Grob K, Lambré C, Lampi E, Mengelers M, Mortensen A, Rivière G, Steffensen IL, Tlustos C, Loveren HV, Vernis L, Zorn H, Aguilera J, Kovalkovicova N, Liu Y, Maia J, Chesson A. Safety evaluation of the food enzyme α-cyclodextrin glucanotransferase from Escherichia coli strain WCM105xpCM703. EFSA J. 2020 Oct 1;18(10):e06248. 10: Ergoren MC, Paolacci S, Manara E, Dautaj A, Dhuli K, Anpilogov K, Camilleri G, Suer HK, Sayan M, Tuncel G, Sultanoglu N, Farronato M, Tartaglia GM, Dundar M, Farronato G, Gunsel IS, Bertelli M, Sanlidag T. A pilot study on the preventative potential of alpha-cyclodextrin and hydroxytyrosol against SARS-CoV-2 transmission. Acta Biomed. 2020 Nov 9;91(13 (13-S):e2020022.
