For decades, berberine has been one of the most studied compounds in metabolic health — and one of the most poorly absorbed. Standard berberine HCL is rapidly metabolized before most of it reaches circulation, which is why meaningful results often require dosing 1,500mg+ per day, with the GI discomfort that comes with it. Arbor Berberine+ was built to solve that problem from the inside out. Each delayed-release capsule delivers GlucoVantage® dihydroberberine — the active downstream metabolite of berberine — at a dose human pharmacokinetic research has shown can produce up to 5× greater plasma berberine exposure than equivalent standard berberine HCL. Less material, more uptake, dramatically better tolerability. Dihydroberberine works at the cellular level by activating AMPK (the body's metabolic master switch) and supporting endogenous GLP-1 secretion — two of the most discussed pathways in modern blood sugar and weight management research. Absorption is only half the formula. Most berberine supplements stop there; Berberine+ adds CoreBiome® tributyrin, a clinically tested butyrate precursor that resists gastric breakdown and releases butyrate along both the small and large intestine, fueling colonocytes and supporting gut barrier integrity. It's a deliberate acknowledgment of the gut-metabolic axis: blood sugar regulation doesn't happen in isolation, and the microbiome plays a measurable role. Rounding out the panel are two of the most well-validated metabolic compounds in the literature: Banaba Leaf Extract standardized to 2% corosolic acid for GLUT4 glucose transporter activation, and Chromium Picolinate (200 mcg) as an essential cofactor for insulin receptor signaling and macronutrient metabolism. The capsule itself is engineered for delayed release, bypassing the stomach so each active lands where it can do the most work. No proprietary blends. No filler dosing. Plant-based, sugar-free, gluten-free, non-GMO, third-party tested, and produced in a GMP-certified U.S. facility. 60 capsules · 30-day supply · two patented branded ingredients · six metabolic pathways — engineered for serious daily use. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
