Pure Encapsulations Calcium-D-Glucarate Supports Detoxification and Healthy Cells Supports detoxification and cellular health. Key Benefits and Features: Ages 18 and up Detoxification and cellular health support Support healthy detoxification Promotes healthy cell structure and function May support lipid metabolism Extensively studied, patented form of glucaric acid Made with high-quality ingredients backed by verifiable science Ingredients Serving Size: 2 Vegetarian Capsules Amount/Serving Calcium-D-glucarate 1,000 mg Other Ingredients: Vegetarian capsule (cellulose, water). Does Not Contain: Wheat, soy, dairy, eggs, tree nuts, peanuts, gluten, artificial colors, flavors, sweeteners, coating, shellacs, GMOs, unnecessary binders, fillers, preservatives, magnesium stearate, trans fat, or hydrogenated oils. Gluten Free, Non-GMO, Vegan, Vegetarian, Hypoallergenic Suggested Use As a dietary supplement, take 2 capsules, 1-3 times daily, with meals. Warning: If you are pregnant or lactating, have any health condition, or are taking any medication, consult your health professional before use. Storage: Store in a cool, dry place. More Info. Researchers at the University of Texas M.D. Anderson Cancer Center, Memorial Sloan-Kettering Cancer Center of New York, AMC Cancer Center in Colorado, and Ohio State University have extensively studied D-glucarate. Calcium-D-Glucarate™, a patented form of glucaric acid, is a nutrient with the potential to support healthy detoxification and cellular function. In the gut and liver, phase II detoxification includes an enzymatic process called glucuronidation, in which toxic compounds are bound to glucuronic acids so that they can be eliminated in a safe form from the body via the bile and/or urine. Beta-glucuronidase is a naturally occurring enzyme found in various organs and cells, which can cleave apart these neutral compounds. D-Glucarate has been shown to help modulate beta-glucuronidase enzyme activity, helping the glucuronide conjugates stay intact, so that they can leave the body.4 D-glucarate may also help to maintain healthy cell structure and function.5 An animal study suggests the promising role of D-glucarate in supporting healthy lipid metabolism. Calcium-d-Glucarate™ is derived from cornstarch and glucose. (United States Patent Nos. 4,845,123; 5,364,644; 5,561,160. European Patent No. 0,528,950.)
