Specification Full name CD27 rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. Swissprot No P26842 Gene Accession BC012160 WB Predicted band size 29 kDa WB Positive control WB Recommended dilution 1000-5000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human thyroid cancer IHC Recommed dilution Recommended dilution: 50-200 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P100709-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or CD27 antigen-treated (Neutralization experiment) using P100709(CD27 Antibody) at dilution 1/60
