Description Deslorelin is a synthetic nonapeptide analogue of the natural gonadotropin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Deslorelin has a molecular weight of 1281.64 Dalton. Summary Deslorelin is being studied in the treatment of cancer as a way to block sex hormones made by the ovaries or testicles. It belongs to the family of molecules known as gonadotropin-releasing hormone analogs. It is used for the induction of ovulation in mares. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Molecular Formula C64H83N17O12 Amino Acid Sequence pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHC2H5 CAS REGISTRY NO. 57773-65-6 Other names Gonadotropin-releasing hormone (GnRH) superagonist, luteinizing hormone-releasing hormone agonist, luteinising hormone-releasing hormone agonist, GnRH agonist, LHRH agonist Type Synthetic peptide Purity Greater than 99.0%. Formulation Sterile-filtered white lyophilized (freeze-dried) powder. The Deslorelin peptide was lyophilized with no additives. Reconstitution It is recommended to reconstitute the lyophilized Deslorelin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. Shipping Shipped at ambient temperature. Upon receipt, store at the temperature recommended below. Storage/Expiration Lyophilized Deslorelin, although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution, Deslorelin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. Usage This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive. Resources Product Datasheet (PDS) Related Products Gonadotropin Hormones
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