Fluorogenic Chymotrypsin Substrate II Catalog number: B2013080 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 5 mg Molecular Weight or Concentration: 661.7 g/mol Supplied as: Lyophilized Powder Applications: molecular tool for various biochemical applications Storage: -20°C Keywords: Chymotrypsin Substrate II, Fluorogenic Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Al-Abdullah IH, Bagramyan K, Bilbao S, Qi M, Kalkum M. Fluorogenic Peptide Substrate for Quantification of Bacterial Enzyme Activities Sci Rep. 2017 Mar 13;7:44321. Nedungadi D, Binoy A, Pandurangan N, Pal S, Nair BG, Mishra N. 6-Shogaol induces caspase-independent paraptosis in cancer cells via proteasomal inhibition Exp Cell Res. 2018 Mar 15;364(2):243-251. Raymond WW, Ruggles SW, Craik CS, Caughey GH. Albumin is a substrate of human chymase. Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site J Biol Chem. 2003 Sep 5;278(36):34517-24. Nehybová T, Šmarda J, Daniel L, Stiborek M, Kanický V, Spasojevič I, Preisler J, Damborský J, Beneš P. Wedelolactone Acts as Proteasome Inhibitor in Breast Cancer Cells Int J Mol Sci. 2017 Mar 29;18(4):729. Nozawa M, Tanizawa K, Kanaoka Y. New chromogenic and fluorogenic substrates for the determination of butyrylcholinesterase and arylesterase activities J Pharmacobiodyn. 1980 Jul;3(7):321-7. Harding CV, France J, Song R, Farah JM, Chatterjee S, Iqbal M, Siman R. Novel dipeptide aldehydes are proteasome inhibitors and block the MHC-I antigen-processing pathway J Immunol. 1995 Aug 15;155(4):1767-75. Le QT, Ohashi A, Hirose S, Katunuma N. Reverse zymography using fluorogenic substrates for protease inhibitor detection Electrophoresis. 2005 Mar;26(6):1038-45. Semashko TA, Lysogorskaia EN, Oksenoĭt ES, Bacheva AV, Filippova IIu. [Chemoenzymatic synthesis of new fluorogenous substrates for cysteine proteases of the papain family] Bioorg Khim. 2008 May-Jun;34(3):376-81. Gohlke S, Kloss A, Tsokos M, Textoris-Taube K, Keller C, Kloetzel PM, Dahlmann B. Adult human liver contains intermediate-type proteasomes with different enzymatic properties Ann Hepatol. 2014 Jul-Aug;13(4):429-38.
