Human Complement C3 Deficient Heparin Plasma Catalog number: B2015128 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 1 mL Molecular Weight or Concentration: N/A Supplied as: Plasma Applications: molecular tool for various biochemical applications Storage: -20° C Keywords: Complement Component 3, Complement Component III, Complement Factor 3 Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Burge J, Nicholson-Weller A, Austen KF. Isolation of C4-binding protein from guinea pig plasma and demonstration of its function as a control protein of the classical complement pathway C3 convertase J Immunol. 1981 Jan;126(1):232-5. Cheng ZZ, Hellwage J, Seeberger H, Zipfel PF, Meri S, Jokiranta TS. Comparison of surface recognition and C3b binding properties of mouse and human complement factor H Mol Immunol. 2006 Mar;43(7):972-9. Sahu SK, Ozantürk AN, Kulkarni DH, Ma L, Barve RA, Dannull L, Lu A, Starick M, McPhatter J, Garnica L, Sanfillipo-Burchman M, Kunen J, Wu X, Gelman AE, Brody SL, Atkinson JP, Kulkarni HS. Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury Sci Immunol. 2023 Feb 3;8(80):eabp9547. Chen P, Yu G, Zhang X, Xie X, Wang J, Shi S, Liu L, Lv J, Zhang H. Plasma Galactose-Deficient IgA1 and C3 and CKD Progression in IgA Nephropathy Clin J Am Soc Nephrol. 2019 Oct 7;14(10):1458-1465. Zhang W, Wang G, Wang Y, Jin Y, Zhao L, Xiong Q, Zhang L, Mou L, Li R, Yang H, Dai Y. Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting Sci Rep. 2017 Jul 10;7(1):5009. Servais A, Noël LH, Frémeaux-Bacchi V, Lesavre P. C3 glomerulopathy Contrib Nephrol. 2013;181:185-93. Durey MA, Sinha A, Togarsimalemath SK, Bagga A. Anti-complement-factor H-associated glomerulopathies Nat Rev Nephrol. 2016 Sep;12(9):563-78. Márquez-Tirado B, Gutiérrez-Tenorio J, Tortajada A, Lucientes Continente L, Caravaca-Fontán F, Malik TH, Roldán Montero R, Elías S, Saiz Gonzalez A, Fernández-Juarez G, Sánchez-Corral P, Pickering MC, Praga M, Rodríguez de Córdoba S, Goicoechea de Jorge E. Factor H-Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy J Am Soc Nephrol. 2022 Jun;33(6):1137-1153. Fakhouri F, de Jorge EG, Brune F, Azam P, Cook HT, Pickering MC. Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice Kidney Int. 2010 Aug;78(3):279-86.
