FDA Approved Joint Support for Horses Product Description LEGEND Injectable Solution is an FDA-approved equine joint therapy used to treat non-infectious synovitis associated with osteoarthritis in horses. It contains hyaluronic acid, which helps reduce joint inflammation, improve synovial fluid quality, and decreases lameness. LEGEND is suitable for horses of any age or discipline and supports joint comfort and mobility. Benefits Reduces inflammation: Helps decrease inflammatory mediators inside the joint to reduce pain and inflammation. Improves joint fluid: Enhances synovial fluid quality to support smoother joint movement and comfort. Decreases lameness: Proven to reduce the degree of lameness associated with equine osteoarthritis. Fast improvement: Clinical improvement can be seen after a single dose in many horses. Flexible administration: Approved for intravenous or intra articular use depending on product strength. Ingredients Active Ingredients Hyaluronic acid as sodium hyaluronate. How to Use Recommended-Dosage Chart Dosage & Administration Instructions Prescription status: This product is prescription only and must be used by or on the order of a licensed veterinarian. Approved route: LEGEND Multi-Dose 20 mL is approved for intravenous use only. Labeled dose: The labeled dose is 4 mL per intravenous treatment. Treatment schedule: Treatment may be repeated at weekly intervals for a total of three treatments. Additional Information Precautions Horse use only: Intended only for horses and not approved for other animal species. Breeding safety: Safety has not been evaluated in breeding stallions or pregnant or lactating mares. Prescription status: This product is available by prescription and must be used under licensed veterinary supervision. Human warning: Not for use in humans and should be kept out of reach of children. Possible Side Effects IV reactions: Occasional lethargy, depression, or fever may occur after intravenous administration. Joint reactions: Lameness, joint swelling, or pain may occur after intra articular administration. Storage Information Temperature limits: Store at or below 77°F with brief excursions allowed up to 104°F. Shipping & Return We offer ground, express, priority, and international delivery; see our shipping policy for details. For return instructions or product concerns, please refer to our detailed refund policy. Prescription items are NON-RETURNABLE and NON-REFUNDABLE. Frequently Asked Questions Q1: What is LEGEND Injectable Solution used for in horses? Ans: LEGEND is used to treat joint dysfunction caused by non-infectious synovitis associated with equine osteoarthritis. It helps reduce inflammation, improve synovial fluid quality, and decrease lameness in horses of all ages and disciplines when administered by a veterinarian. Q2: How does hyaluronic acid help horse joints? Ans: Hyaluronic acid improves joint lubrication, reduces inflammatory mediators, and supports healthier synovial fluid. These actions help protect joint tissues and improve comfort and mobility in horses affected by osteoarthritis or joint inflammation. Q3: Can LEGEND be given intravenously or into the joint? Ans: Yes, administration depends on the product variant. LEGEND 4 mL and Multi Dose 20 mL are approved for intravenous use only, while LEGEND 2 mL is approved for both intravenous and intra articular administration. Q4: Is LEGEND safe for long term joint management? Ans: LEGEND has been used for over 25 years with millions of doses administered. Clinical studies show it is safe and effective when used as directed by a veterinarian for managing equine joint inflammation and lameness.
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