Multi-dose IV joint support for equine osteoarthritis Product Description Legend Multi-Dose Injectable Solution is a sterile, prescription equine product used to treat joint dysfunction of the carpus or fetlock associated with non-infectious synovitis and osteoarthritis. It contains hyaluronate sodium (10 mg/mL) and is approved for intravenous use only. A veterinarian administers treatment to support joint lubrication, comfort, and mobility. Benefits IV-Only Use: Approved for intravenous administration in horses by veterinarians. Joint Support: Helps treat carpus or fetlock dysfunction from osteoarthritis-related synovitis. Multi-Dose Vial: 20 ml vial supports multiple 4 ml treatments. Hyaluronate Sodium: Contains 10 mg/mL hyaluronate sodium for consistent dosing. Performance Ready: Supports comfort and mobility as part of a veterinary plan. Ingredients Active Ingredients - Hyaluronate sodium. How to Use Dosage & Administration Instructions Prescription status: This product is prescription only and must be used by or on the order of a licensed veterinarian. Approved route: LEGEND Multi-Dose 20 mL is approved for intravenous use only. Labeled dose: The labeled dose is 4 mL per intravenous treatment. Treatment schedule: Treatment may be repeated at weekly intervals for a total of three treatments. Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet. Additional Information Precautions Horse use only: Intended for use only in horses and not approved for other species. Breeding safety: Safety has not been evaluated in breeding stallions or pregnant or lactating mares. Human warning: Not for use in humans and should be kept out of reach of children. Possible Side Effects IV reactions: Occasional lethargy, depression, or fever may occur after intravenous administration. Storage Information Temperature control: Store at or below 77°F with brief excursions permitted up to 104°F. Shipping & Returns We offer ground, express, priority, and international delivery; see our shipping policy for details. For return instructions or product concerns, please refer to our detailed refund policy. Prescription items are NON-RETURNABLE and NON-REFUNDABLE. Frequently Asked Questions Q1: What is Legend Multi-Dose Injectable Solution used for? Ans: Legend Multi-Dose is used in horses to treat joint dysfunction of the carpus or fetlock associated with non-infectious synovitis and equine osteoarthritis. It is administered intravenously by a veterinarian to support joint lubrication, comfort, and mobility. Q2: What is the concentration of Legend Multi-Dose 20 ml? Ans: Legend Multi-Dose contains hyaluronate sodium at a concentration of 10 mg/mL. This concentration allows the labelled 4 mL dose to deliver 40 mg of hyaluronate sodium per intravenous treatment when used as directed. Q3: What is the correct dose for Legend Multi-Dose? Ans: The labelled dose for Legend Multi-Dose is 4 ml (40 mg) administered intravenously. Intravenous treatment may be repeated at weekly intervals for a total of three treatments, based on veterinary assessment and the horse’s clinical response. Q4: Is Legend Multi-Dose approved for intra-articular injection? Ans: No. Legend Multi-Dose 20 ml is approved for intravenous use only. If intra-articular therapy is being considered, the veterinarian should follow the labeling for the appropriate product presentation and route and use proper technique. Q5: What are the inactive ingredients in Legend Multi-Dose? Ans: Legend Multi-Dose contains sodium chloride, sodium phosphate dibasic, sodium phosphate monobasic, and benzyl alcohol. These are formulation components listed for the multi-dose vial, along with the active ingredient hyaluronate sodium. Q6: How many treatments are in a 20 ml multi-dose vial? Ans: A 20 ml vial can supply up to five 4 ml doses when used correctly. Actual usable doses depend on proper aseptic withdrawal technique, veterinary handling, and clinic protocols to maintain sterility and minimize product loss. Q7: What side effects can occur after Legend administration? Ans: Some horses may experience occasional depression, lethargy, or fever following administration. Severe reactions are uncommon, but horses should be monitored after treatment. Contact a veterinarian if symptoms persist, worsen, or if the horse’s condition changes. Q8: Can Legend Multi-Dose be used in pregnant or breeding horses? Ans: Safety has not been evaluated in breeding stallions or in pregnant or lactating mares. A veterinarian should weigh benefits and risks for these horses and decide whether Legend Multi-Dose is appropriate based on clinical need and management goals.
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