Specification Full name MAP3K7 rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. Swissprot No O43318 Gene Accession BC017715 WB Predicted band size 67 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human liver cancer IHC Recommed dilution Recommended dilution: 200-300 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P108924-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or MAP3K7 antigen-treated (Neutralization experiment) using P108924(MAP3K7 Antibody) at dilution 1/150
