Methyl Active B™ is a super B complex with a potent combination of 2 methylated B vitamins, 6 active B vitamins & 2 essential co-factors in water-soluble forms. Methylated B Vitamins included: Quatrefolic® Folate (Patented Methylated Vitamin B9) MecobalActive® Methylcobalamin (Patented Methylated Vitamin B12) Active-Form B Vitamins Include: Thiamine & BenfoPure® Benfotiamine (Patented & Active Forms of Vitamin B1) Riboflavin 5'-Phosphate Sodium (Active Form of Vitamin B2) Niacin & Niacinamide (2 Active Forms of Vitamin B3) D-Calcium Pantothenic Acid (Active form of Vitamin B5) Pyridoxal 5'-Phosphate (Active Co-Enzyme Form of Vitamin B6) Biotin (Active Form of Vitamin B7) Essential B Vitamin CoFactors: Trimethylglycine (TMG) VitaCholine® Choline Dihydrogen Citrate (Choline) These B vitamins support whole-body health and are particularly implicated in supporting the following body systems: Energy production Brain & nervous system Heart & vascular system Liver & detoxification Hair, skin & nails DirectionsTake two (2) capsules once or twice daily, or as directed by a healthcare practitioner. If detox symptoms occur, lower the dose to one (1) capsule and slowly increase to the full dose. Please NoteOur formula contains a small amount of Niacin, a beneficial B Vitamin. Niacin can sometimes cause a "flush"—a temporary warm, tingling sensation on the skin that may last from a few minutes to a few hours, depending on your metabolism. Our dosing is conservative, and most people tolerate it very well without experiencing the flush. While some individuals may experience a temporary flush, this is generally well-tolerated and is not harmful. The flush tends to decrease with regular use. Research suggests that the flush may help empty mast cells of histamine, which can be beneficial. Additionally, the flush tends to lessen and stabilize with regular use, meaning you might find this sensation less noticeable over time. To learn more about the benefits and safety of niacin, we recommend the book Niacin: The Real Story by Abram Hoffer. Safety InformationIndividuals taking medication, children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged. StorageKeep tightly closed in a cool, dry place. Do not discard desiccant. Refrigeration recommended in hot or humid climates and when storing in a pill container to maintain optimal quality and freshness. Best used within 2 months of opening. Keep out of reach of children. IndicationsSupports adrenal, neurological & cardiovascular health* IngredientsThiamine (as Thiamine HCl) 20 mg, Riboflavin (as Riboflavin 5’-Phosphate Sodium) 20 mg, Niacin (as 120 mg Niacinamide and 20 mg Niacin) 140 mg, Vitamin B6 (as Pyridoxal 5’-Phosphate) 20 mg, Folate (as Quatrefolic® (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 680 mcg DFE, Vitamin B12 (as MecobalActive® Methylcobalamin) 400 mcg, Biotin 400 mcg, Pantothenic Acid (as D-Calcium Pantothenate) 150 mg, Choline (as VitaCholine® Choline Dihydrogen Citrate) 30 mg, Trimethylglycine (TMG) 50 mg, BenfoPure® Benfotiamine 20 mg. Other Ingredients: Acid-Resistant Capsule (Hypromellose), Bamboo Extract. Formulated to ExcludeFillers, gluten, wheat, soy, corn allergens, yeast, animal or dairy products, sesame, shellfish, fish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial preservatives, sweeteners or colors. All Pure TheraPro Rx Formulas Meet or Exceed cGMP Quality Standards. This product is manufactured in the United States in an NSF and GMP-certified facility. Quatrefolic® is a registered trademark of Gnosis SPA Corp. Produced under US Patent 7,947,662. MECOBALACTIVE® is a trademark of HEALTHTECH BIO ACTIVES, S.L.U. BenfoPure® trademark of Hamari Chemicals, Ltd. Vitacholine® is a registered trademark of Balchem Corp.