What is MoxiSolv™ Injection? MoxiSolv Injection (moxidectin) is a ready-to-use, sterile solution containing 1% moxidectin. Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones. MoxiSolv Injection Is specially formulated to allow moxidectin to be absorbed from the site of injection and distributed internally to the areas of the body affected by endo- and/or ectoparasitism. Moxidectin binds selectively and with high affinity to glutamate-gated chloride ion channels which are critical to the function of invertebrate nerve and muscle cells. This interferes with neurotransmission resulting in paralysis and elimination of the parasite. Indications MoxiSolv Injection, when administered at the recommended dose level of 0.2 mg/2.2 lb (0.2 mg/kg) body weight, is effective in the treatment and control of the following internal and external parasites of cattle: Gastrointestinal Roundworms Ostertagia ostertagi(adults and fourth-stage larvae)(including inhibited Larvae) Haemonchus placei(adults only) Trichostrongylus axei(adults and fourth-stage larvae) T. colubriformis(adults and fourth-stage larvae) Cooperia oncophora(adults only) C. punctata(adults and fourth-stage larvae) C. pectinata(adults only) C. spatulata(adults only) C. surnabada(adults and fourth-stage larvae) Nematodirus helevtianus(adults only) Oesophagostomum radiatum(adults and fourth-stage larvae) Trichuris spp.(adults only) Lungworms Dictyocaulus viviparus(adults and fourth-stage larvae) Cattle Grubs Hypoderma bovis H. lineatum Mites Psoroptes ovis(syn. P. communis var. bovis) Sucking Lice Linognathus vituli Solenopotes capillatus Benefits FDA-approved bioequivalent to Cydectin® Injection Ready-to-use injectable parasiticide containing 1% moxidectin for use in beef and non-lactating dairy cattle Dosage: 1mL / 110 lbs bodyweight Long-lasting, persistent activity against key internal parasites Short pre-slaughter withdrawal period as compared to other injectable dewormers (21 days) Dung beetle friendly – a healthy population of dung beetles is environmentally beneficial but will also help you in your efforts to control internal and external parasites by reducing breeding environments for horn flies and exposure to gastrointestinal nematodes The only moxidectin injectable product available in 500mL plastic bottle Withdrawal Period Cattle must not be slaughtered for human consumption within 21 days of treatment. Important Safety Information This drug is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows.A withdrawal period has not been established for pre-ruminating calves.Do not use in calves to be processed for veal.