Introduction HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) is a zwitterionic sulfonic acid buffering agent; one of the twenty Good's buffers. HEPES is widely used in cell culture, largely because it is better at maintaining physiological pH despite changes in carbon dioxide concentration (produced by aerobic respiration) when compared to bicarbonate buffers, which are also commonly used in cell culture. GMP Grade PAN-Biotech HEPES Buffer 1 M GMP Grade is a ready-to-use, highly concentrated buffer solution designed for direct use in GMP-regulated clinical and industrial applications. The GMP grade version is based on the proven HEPES formulation and is manufactured under strictly controlled GMP conditions. Defined raw materials, high batch-to-batch consistency and comprehensive documentation make HEPES Buffer 1 M GMP a true ready-to-use solution, suitable for immediate implementation in sensitive cell culture and manufacturing workflows. Applications pH stabilization of cell culture media under GMP conditions. Clinical cell processing and cell therapy. Cell and gene therapy workflows. Biopharmaceutical development and manufacturing. Features Manufactured in compliance with Good Manufacturing Practice (GMP). Ready-to-use – immediately applicable. High batch-to-batch consistency and process reliability. Composition HEPES 238.31 g/L Specifications Cat. No. CT-01100 Quality: GMP Grade (EU Annex 1) Liquid / Powder: Liquid Product Category: Media supplements Product Type: HEPES Size: 100 ml Sterile: Yes Storage Temperature: +2°C - +8°C Manufacturer: PAN-Biotech GmbH Country of Origin: Germany Documents Material Safety Data Sheet (MSDS) PAN-Biotech GMP Product Factsheet Related Products RUO Version: PAN-Biotech HEPES Buffer 1 M PAN-Biotech GMP Grade Cell Culture Products Ilex Life Sciences LLC is an authorized distributor of PAN-Biotech products.