Controls Urinary Incontinence in Dogs with Weak Sphincter Product Description Proin Chewable Tablets for Dogs contain phenylpropanolamine hydrochloride, a veterinary medication used to help control urinary incontinence caused by urethral sphincter hypotonus. The chewable tablets work by increasing urethral muscle tone, helping dogs maintain better bladder control. Proin is commonly prescribed by veterinarians and is formulated for oral administration to support dogs experiencing urine leakage. *Signature Is Required Upon Delivery In The Following States: Arkansas, Illinois, Iowa, Louisiana, Oregon, West Virginia. Please note that the product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference. Benefits Supports Bladder Control: Helps manage urinary incontinence in dogs caused by urethral sphincter hypotonus and reduces accidental urine leakage episodes. Enhances Urethral Strength: It activates adrenergic receptors, which helps tighten the smooth muscles of the urethra and bladder neck, improving their ability to hold urine. Veterinary Prescribed Treatment: Formulated specifically for canine use and legally restricted for administration under veterinary guidance. Convenient Chewable Tablets: Flavored chewable tablets designed for oral administration, making it easier for many dogs to accept the medication. Variants 25 mg 50 mg 75 mg Ingredients Composition Table Ingredient Quantity Phenylpropanolamine Hydrochloride 25 mg Phenylpropanolamine Hydrochloride 50 mg Phenylpropanolamine Hydrochloride 75 mg How to Use Recommended-Dosage Chart Body Weight Recommended Dose Frequency Based on body weight 2 mg/kg (0.91 mg/lb) Twice daily Tablet adjustment Dose calculated in half-tablet increments As prescribed by veterinarian Dosage & Administration Instructions Veterinary Prescription: This medication is restricted for use only by or on the order of a licensed veterinarian. Weight-Based Dosage: Administer orally at a total recommended dosage of 2 mg per kilogram body weight twice daily. Tablet Adjustment: Tablets are scored and dosage should be calculated in half-tablet increments when determining the correct dose. Follow Veterinary Guidance: Always administer Proin exactly according to dosage instructions provided by your veterinarian for your dog. Missed Dose Advice: If you forget a dose, give it when you remember, unless the next scheduled dose time is very close. Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet. Additional Information Precautions Provide Fresh Water: Increased thirst may occur during treatment, so dogs should always have access to adequate fresh water. Avoid Overdose Risk: Store tablets securely since dogs may chew through bottles and accidentally consume multiple tablets. Use With Caution: Use carefully in dogs with heart disease, hypertension, kidney disease, liver disease, diabetes, or glaucoma. Drug Interaction Risk: Use cautiously with sympathomimetic drugs, tricyclic antidepressants, monoamine oxidase inhibitors, or halogenated anesthetics. Breeding Safety Unknown: The safety of Proin has not been evaluated in breeding dogs, pregnant dogs, or lactating females. Possible Side Effects Digestive Upset: Some dogs may experience vomiting, diarrhea, reduced appetite, or hypersalivation during treatment. Behavior Changes: Anxiety, agitation, confusion, vocalization, or lethargy have been reported in some treated dogs. Blood Pressure Increase: Hypertension may occur due to the medication’s adrenergic activity affecting cardiovascular function. Weight Changes: Some dogs may experience noticeable weight loss during treatment with phenylpropanolamine. Neurologic Symptoms: Tremors, seizures, or coordination problems have occasionally been reported in post-approval safety reports. Storage Information Temperature control: Store the tablets at 20°C to 25°C to maintain their stability. Temperature limits: Temporary shifts between 15°C - 40°C are allowed during storage. Storage safety: Keep tablets stored securely to prevent accidental pet ingestion. Keep Away Children: This medication is not intended for human use and should always be kept away from children. Shipping & Return We offer ground, express, priority, and international delivery; see our shipping policy for details. For return instructions or product concerns, please refer to our detailed refund policy. Prescription items are NON-RETURNABLE and NON-REFUNDABLE. Frequently Asked Questions Q1: What is Proin used for in dogs? Ans: Proin Chewable Tablets are prescribed to help control urinary incontinence in dogs caused by urethral sphincter hypotonus. The medication increases urethral muscle tone, which helps improve bladder control and reduces urine leakage episodes in affected dogs. Q2: How long does Proin take to start working in dogs? Ans: Phenylpropanolamine, the active ingredient in Proin, is absorbed after oral administration and may begin acting within approximately 15 to 30 minutes. However, improvement in urinary incontinence may take several days of treatment as the medication helps increase urethral muscle tone. Q3: How should Proin tablets be given to dogs? Ans: Proin tablets are administered orally at a recommended dosage of 2 mg per kilogram of body weight twice daily. The tablets are scored so doses can be adjusted in half tablet increments.Be sure to give the medication exactly as your veterinarian directs. Q4: Are there any side effects of Proin in dogs? Ans: Some dogs may experience side effects such as vomiting, loss of appetite, weight loss, increased thirst, lethargy, or behavioral changes. In certain cases, hypertension or digestive upset may occur. Pet owners should contact their veterinarian if unusual symptoms appear. Q5: How should Proin Chewable Tablets be stored? Ans: Store Proin tablets at room temperature between 20°C and 25°C, although brief temperature changes from 15°C to 40°C are permitted. Because the tablets are flavored and dogs may consume multiple tablets, the medication must be kept in a secure location. References: https://www.prnpharmacal.com/wp-content/uploads/2021/02/Proin-Legal.pdf https://www.prnpharmacal.com/products/pharmaceuticals/proin/
