.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}} Description BDNF (Brain-Derived Neurotrophic Factor) is a neurotrophic factor belonging to the neurotrophin family, characterized by a conserved cysteine knot structure and sharing homology with other neurotrophins such as NGF and NT-3. It is widely expressed in the central and peripheral nervous systems, with particularly high concentrations in brain regions like the hippocampus and cerebral cortex. BDNF plays crucial roles in neural growth, survival, synaptic plasticity, and cognitive function. It inhibits apoptotic pathways and enhances neuronal survival under conditions of serum deprivation or stress. When combined with factors like retinoic acid, BDNF can induce the differentiation of neural stem cells (NSCs) or PC12 cells into neurons. Specifications Product Details Cat. No. Y00201 Purity ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). Endotoxin ≤10 EU/mg by the LAL method. Bioactivity The activity is determined by the dose-dependent proliferation of C6 cell sand is typically between 0.5-1.5 μg/mL. Corresponding to a specific activity of 1 x 103 units/mg. Accession P23560 Species Human Expression System CHO Mol. Weight 13.5 kDa Expression Region His129-Arg247 Tag Info Tag Free Formulation Lyophilized Buffer Lyophilized from a 0.22 μm filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4. Size 10μg/50μg/1mg Lead Time Products are in stock, but custom products may require further consultation. Reconstitution It is recommended to redissolve in sterile deionized water. Shipping The product is shipped with blue ice. Storage & Stability 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Features ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results. ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells. ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches. ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements. Applications Stem Cell Research Supports survival and differentiation of neural stem cells. Cell Biology Regulates neuronal survival, differentiation, and synaptic plasticity. Data Figures Figure 1: The activity is determined by the dose-dependent proliferation of C6 cell sand is typically between 0.5-1.5 μg/mL. Corresponding to a specific activity of 1 x 103 units/mg. Instructions for Use Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use. Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results. Do not mix with other similar products to avoid cross-reactivity and potential interference. Cautions • Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications. • Preservation: Handle according to instructions to preserve its activity and stability. • Support: Contact our technical support team if you encounter any issues or questions. Documents 📄 Download COA
