.biofargo-table-wrapper {overflow-x: auto;margin: 20px 0;-webkit-overflow-scrolling: touch;}.biofargo-spec-table {width: 100%;border-collapse: collapse;border: 1px solid #dee2e6;min-width: 600px;background: #fff;}.biofargo-spec-table th,.biofargo-spec-table td {border: 1px solid #dee2e6;padding: 12px;vertical-align: middle;white-space: normal;word-break: break-word;}@media (max-width: 600px) {.biofargo-table-wrapper {border: 1px solid #eee;border-radius: 8px;padding: 6px;background: #fff;}.biofargo-spec-table {min-width: 720px;}} Description PDGF-AA (Platelet-Derived Growth Factor-AA), a subtype of the platelet-derived growth factor (PDGF) family, consists of two identical A chains. It primarily regulates cellular processes such as proliferation, migration, differentiation, and survival by activating tyrosine kinase receptors on the cell membrane (PDGFR-αα, PDGFR-αβ, or PDGFR-ββ). PDGF-AA specifically binds to the PDGFR-αα receptor and stimulates the proliferation of specific cell types, including fibroblasts, glial cells, and mesenchymal stem cells (MSCs), making it widely used for expanding primary or hard-to-culture cells. In wound healing and tissue engineering research, PDGF-AA can induce directed cell migration to mimic in vivo repair processes. For certain mesenchymal stem cells or neural precursor cells, it helps maintain their undifferentiated state or promotes directed differentiation—such as toward osteogenic or glial lineages. Specifications Product Details Cat. No. Y07001H Purity ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). Endotoxin ≤10 EU/mg by the LAL method. Bioactivity The bioactivity is determined by the dose-dependent proliferation of NIH3T3 cells is typically between ≤5.0 ng/mL. Accession P04085 Alternative Names Platelet-derived growth factor subunit A; PDGF-1 Species Human Expression System CHO Target Protein Sequence Ser87-Thr211 Mol. Weight 14.3kDa Tag Info Tag free Formulation Lyophilized Buffer PBS, 5% Mannitol and 0.01% Tween 80, pH7.4. Size 10μg/50μg/1mg Lead Time Products are in stock, but custom products may require further consultation. Reconstitution It is recommended to redissolve in sterile deionized water. Shipping The product is shipped with blue ice. Storage & Stability 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Features ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results. ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells. ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches. ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements. Applications Stem Cell Research Supports mesenchymal stem cell proliferation and migration. Cell Biology Stimulates fibroblast proliferation, migration, and tissue remodeling. Data Figures Figure 1: Measured in a cell proliferation assay using NIH3T3 cells. Instructions for Use Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use. Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results. Do not mix with other similar products to avoid cross-reactivity and potential interference. Cautions • Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications. • Preservation: Handle according to instructions to preserve its activity and stability. • Support: Contact our technical support team if you encounter any issues or questions. Documents 📄 Download COA
