SUMO Protease Catalog number: B2014284 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 1000 units Molecular Weight or Concentration: 27 kDa Supplied as: Solution Applications: molecular tool for various biochemical applications Storage: −20°C Keywords: Small Ubiquitin-like Modifier Protease, ULP, Ubiquitin like protease, Ubiquitin-homology domain protein PIC1, Ubl-specific protease Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Li H, Chen L, Li Y, Hou W. SUMO-specific protease 1 inhibitors-A literature and patent overview Expert Opin Ther Pat. 2022 Dec;32(12):1207-1216. Guerrero F, Ciragan A, Iwa H. Tandem SUMO fusion vectors for improving soluble protein expression and purification Protein Expr Purif. 2015 Dec;116:42-9. Cheng JK. [SUMO-specific protease 1 and cancer] Ai Zheng. 2008 Jul;27(7):771-4. Waters E, Wilkinson KA, Harding AL, Carmichael RE, Robinson D, Colley HE, Guo C. The SUMO_protease SENP3 regulates mitochondrial autophagy mediated by Fis1 EMBO Rep. 2022 Feb 3;23(2):e48754. Barry R, John SW, Liccardi G, Tenev T, Jaco I, Chen CH, Choi J, Kasperkiewicz P, Fernandes-Alnemri T, Alnemri E, Drag M, Chen Y, Meier P. SUMO-mediated regulation of NLRP3 modulates inflammasome activity Nat Commun. 2018 Aug 1;9(1):3001. Nishida T. SUMO-specific protease SENP3 enhances MDM2-mediated ubiquitination of PARIS/ZNF746 in HeLa cells Biochem Biophys Res Commun. 2022 Jul 30;615:150-156. Kuo D, Nie M, Courey AJ. SUMO as a solubility tag and in vivo cleavage of SUMO fusion proteins with Ulp1 Methods Mol Biol. 2014;1177:71-80. Chauhan KM, Chen Y, Chen Y, Liu AT, Sun XX, Dai MS. The SUMO-specific protease SENP1 deSUMOylates p53 and regulates its activity J Cell Biochem. 2021 Feb;122(2):189-197. Leach CA, Tian X, Mattern MR, Nicholson B. Detection and characterization of SUMO protease activity using a sensitive enzyme-based reporter assay Methods Mol Biol. 2009;497:269-81.
