Active Folate for Methylation, Mood & Cellular Health Thorne 5-MTHF provides L-5-methyltetrahydrofolate, the biologically active form of folate (vitamin B9) that your body can use immediately—without needing conversion. Unlike synthetic folic acid, 5-MTHF bypasses the MTHFR conversion pathway, making it especially useful for individuals who have difficulty converting folic acid into its active form. Folate plays a critical role in: DNA synthesis and cell division Red blood cell production Neurotransmitter production (serotonin, dopamine, etc.) This makes 5-MTHF a key nutrient for brain function, mood balance, cardiovascular health, and overall cellular performance. Longevity Brain & Cellular Health Recovery Energy & Nervous System Support Detox Methylation & Cellular Support a:hover div { border-color: #000; transform: translateY(-2px); }