HieffTM RNAiBoost in vitro transfection reagent relies on an exclusive delivery platform to efficiently and precisely deliver siRNA into cells, achieving >90% target gene silencing even in hard-to-transfect systems such as primary cells, with operation completed in 5 minutes, specifically designed for knockdown in primary and other hard-to-transfect cell lines, compatible with serum and antibiotics, and no medium change required post-transfectionWrite information about product introduction. Features Higher transfection efficiency: Achieves >90% target gene knockdown even in hard-to-transfect primary cells Lower siRNA requirement: Delivers high knockdown efficiency with siRNA concentrations as low as 2–50 nM Simplified workflow: Complex formation in just 5 minutes; fully compatible with serum and antibiotics—no media change required Components Components No. Name 40807ES01 40807ES03 40807ES04 40807-A RNAiBoost Transfection Reagent 100 μL 0.75 mL 1.5 mL 40807-B Enhancer 300 μL 3 × 0.75 mL 3 × 1.5 mL Storage This product should be stored at 2~8℃ for 1 years. Figures High Knockdown Efficiency Figure 1. siRNA transfection across different cells using Booster DNA&RNA Transfection Reagent versus supplier T*. The result demonstrates superior siRNA transfection efficiency of Booster. Figure 2: Hard-to-Transfect Cell Lines-STC-1 Figure 3: Hard-to-Transfect Cell Lines-HepG2 Figure 4: Hard-to-Transfect Cell Lines-HK-2 Customer Cases: Primary Cell Transfection Cases Cell Type Abbreviation Nucleic Acid Type Primary bone marrow-derived macrophages BMDM siRNA((6-Well Plate) Primary human umbilical vein endothelial cells HUVEC siRNA Primary bone marrow-derived macrophages BMDM siRNA(12-Well Plate) Tumor Cell Transfection Cases Cell Type Abbreviation Nucleic Acid Type Human T-cell leukemia cell CEMT-4 siRNA Human hepatocellular carcinoma cell line HePG2 siRNA Human breast cancer cell MCF-7 siRNA Human monocytic leukemia cell(induced.to-MO-Macrophages) THP-1 siRNA Human monocytic leukemia cell(and-induced-to-MO-Macrophages) THP-1 siRNA Human-Monocytic·Leukemia-Cell THP-1 siRNA Mouse-Lung-Carcinoma-Cell LLC siRNA Human·Histiocytic·Lymphoma-Cell U937 siRNA Tissue Cell Transfection Cases Cell Type Abbreviation Nucleic Acid Type Human bronchial epithelial cell BEAS-2B siRNA Human renal proximal tubular epithelial cell HK-2 siRNA Rat-Cardiomyocyte H9c2 siRNA Human-Embryonic-Kidney-Cell HEK293 siRNA Human hepatic stellate cell LX2 siRNA Mouse cardiac fibroblast MCF siRNA Mouse embryonic fibroblast NIH-3T3 siRNA Mouse monocyte/macrophage cell RAW264.7 siRNA(6-Well Plate) Mouse monocyte/macrophage cell RAW264.7 siRNA(24-Well Plate) Rat bile duct epithelial cell RBE siRNA Mouse intestinal endocrine cell STC1 siRNA Try it for free! Get a free sample of RNAiBoost and validate its performance in your own lab.👉 [Request Sample Now]. Worldwide Shipping! Documents: Safety Data Sheet 40807_MSDS_HB260203_EN.PDF Manuals 40807_Manual_Ver.EN20260203.pdf Related Blog Next-Gen siRNA Transfection | Achieve 90% Gene Knockdown with Ease DNA Transfection? The novel reagent here.