SB-431542 (SB431542), a known Src family kinase inhibitor, is also a potent and selective inhibitor of ALK5 (IC50: 94 nM) and ALK4 (IC50: 140 nM). SB-431542 inhibits the TGF-β-mediated activation of SMAD proteins, expression of collagen and fibronectin, cell proliferation and cell motility, and effectively blocks the transforming growth factor-β1-induced cell migration and invasion. Features Purity≥98% Standardized production, using factory mass production mode Specifications Cat.No. 53004ES08/53004ES10/53004ES50 Size 5 mg/10 mg/50 mg Synonym SB431542, SB 431542 Target ALK5 CAS No. 301836-41-9 Molecular formula C22H16N4O3 Molecular weight 384.39 Appearance Powder Purity ≥98% Solubility Soluble in DMSO Structure Components Components No. Name 53004ES08 53004ES10 53004ES50 53004 SB-431542 5 mg 10 mg 50 mg Shipping and Storage The SB-431542 products should be stored at -15～-25℃ for 2 years. Avoid repeated freeze-thaw cycles. Documents: Safety Data Sheet 53004_MSDS_HB20250210 _EN.pdf Manuals 53004_Manual_HB20250210 _EN.pdf
