Interleukin 7 (IL-7) is a 25 kDa cytokine in the hematopoietin family that plays an important role in lymphocyte differentiation, proliferation and survival. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% aa sequence identity with human, equine, bovine, sheep, porcine, feline and canine IL-7. Human and mouse IL-7 exhibit cross-species activity.IL-7 is produced by a variety of cells in primary and secondary lymphoid tissues, including thymus, bone marrow, and stromal epithelial cells of the intestinal tract.IL-7 contributes to the maintenance of all initial T cells and memory T cells, primarily through the promotion of the expression of the anti-apoptotic protein Bcl-2. IL-7 is essential for T cell development but not for B cell development. This product is supplied as Liquid, high activity, high purity, low endotoxin, No labeling. Product Properties Synonyms Mouse IL7; mIL-7; IL-7interleukin-7; interleukin 7; Lymphopoietin-1; PBGF Species Mouse Source HEK293 Ceslls Sequence Glu26-Ile154 Accession P10168 Tag No Predicted molecularmass 14.9 KDa Endotoxin 95%, determined by SDS-PAGE Activity Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 0.15-0.3 ng/mL Formulation Dissolved in sterile PBS buffer. Appearance Liquid Shipping and Storage -85~-65℃ storage, valid for 1 year after receipt. Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃. Cautions 1. For your safety and health, please wear lab coat and disposable gloves. 2. This product is for scientific research purposes only.
