Calpain Substrate III Fluorogenic Catalog number: B2014006 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 1 mg Molecular Weight or Concentration: 1675.9 g/mol Supplied as: Powder Applications: molecular tool for various biochemical applications Storage: −20°C Keywords: Calpain Substrate III, Fluorogenic Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Goll DE, Thompson VF, Li H, Wei W, Cong J. The calpain system Physiol Rev. 2003 Jul;83(3):731-801. Nakazawa T, Shimura M, Mourin R, Kondo M, Yokokura S, Saido TC, Nishida K, Endo S. Calpain-mediated degradation of G-substrate plays a critical role in retinal excitotoxicity for amacrine cells J Neurosci Res. 2009 May 1;87(6):1412-23. Liu Y, Che X, Zhang H, Fu X, Yao Y, Luo J, Yang Y, Cai R, Yu X, Yang J, Zhou MS. CAPN1 (Calpain1)-Mediated Impairment of Autophagic Flux Contributes to Cerebral Ischemia-Induced Neuronal Damage Stroke. 2021 May;52(5):1809-1821. Bordone L, Campbell C. DNA ligase III is degraded by calpain during cell death induced by DNA-damaging agents J Biol Chem. 2002 Jul 19;277(29):26673-80. Siman R, Baudry M, Lynch G. Brain fodrin: substrate for calpain I, an endogenous calcium-activated protease Proc Natl Acad Sci U S A. 1984 Jun;81(11):3572-6. Belcastro AN, Shewchuk LD, Raj DA. Exercise-induced muscle injury: a calpain hypothesis Mol Cell Biochem. 1998 Feb;179(1-2):135-45. Ali MA, Stepanko A, Fan X, Holt A, Schulz R. Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity Biochem Biophys Res Commun. 2012 Jun 22;423(1):1-5. Garcia M, Bondada V, Geddes JW. Mitochondrial localization of mu-calpain Biochem Biophys Res Commun. 2005 Dec 16;338(2):1241-7. Kurbatskaya K, Phillips EC, Croft CL, Dentoni G, Hughes MM, Wade MA, Al-Sarraj S, Troakes C, O’Neill MJ, Perez-Nievas BG, Hanger DP, Noble W. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain Acta Neuropathol Commun. 2016 Mar 31;4:34.
