Human Recombinant FGF Basic Catalog number: B2017094 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 500 ug Molecular Weight or Concentration: N/A Supplied as: Solution Applications: a molecular tool for various biochemical applications Storage: -80C Keywords: Human recombinant FGF Basic Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Benington LR, Rajan G, Locher C, Lim LY. Stabilisation of Recombinant Human Basic Fibroblast Growth Factor (FGF-2) against Stressors Encountered in Medicinal Product Processing and Evaluation Pharmaceutics. 2021 Oct 21;13(11):1762. Lee TH, Kim WT, Ryu CJ, Jang YJ. Optimization of treatment with recombinant FGF-2 for proliferation and differentiation of human dental stem cells, mesenchymal stem cells, and osteoblasts Biochem Cell Biol. 2015 Aug;93(4):298-305. Wang X, Hui Q, Jin Z, Rao F, Yu B, Jin L, Banda J, Li X. Progress on the application of growth factor-related drugs in ophthalmology Zhejiang Da Xue Xue Bao Yi Xue Ban. 2022 Nov 25;51(5):626-633. Okumura M, Yajima M, Nishimura T, Ikeda H, Nishimori T. General pharmacology of recombinant human basic fibroblast growth factor Arzneimittelforschung. 1996 Jul;46(7):727-39. Madry H, Kohn D, Cucchiarini M. Direct FGF-2 gene transfer via recombinant adeno-associated virus vectors stimulates cell proliferation, collagen production, and the repair of experimental lesions in the human ACL Am J Sports Med. 2013 Jan;41(1):194-202. Amini M, Venkatesan JK, Nguyen TN, Liu W, Leroux A, Madry H, Migonney V, Cucchiarini M. rAAV TGF-β and FGF-2 Overexpression via pNaSS-Grafted PCL Films Stimulates the Reparative Activities of Human ACL Fibroblasts Int J Mol Sci. 2023 Jul 6;24(13):11140. Morscheid YP, Venkatesan JK, Schmitt G, Orth P, Zurakowski D, Speicher-Mentges S, Menger MD, Laschke MW, Cucchiarini M, Madry H. rAAV-Mediated Human FGF-2 Gene Therapy Enhances Osteochondral Repair in a Clinically Relevant Large Animal Model Over Time In Vivo Am J Sports Med. 2021 Mar;49(4):958-969. Keum BR, Kim HJ, Kim GH, Chang DG. Osteobiologies for Spinal Fusion from Biological Mechanisms to Clinical Applications: A Narrative Review Int J Mol Sci. 2023 Dec 11;24(24):17365. Maloof P, Wang Q, Wang H, Stein D, Denny TN, Yahalom J, Fenig E, Wieder R. Overexpression of basic fibroblast growth factor (FGF-2) downregulates Bcl-2 and promotes apoptosis in MCF-7 human breast cancer cells Breast Cancer Res Treat. 1999 Jul;56(2):153-67.
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