Description PAN-Biotech Panexin Basic is a fully defined serum replacement for the cultivation of adherent and non-adherent cells under serum-free culture conditions or to significantly reduce the amount of serum in cell culture. It supports the growth of many cell types in an optimum manner without any extra handling compared to serum. A GMP Grade version is now available: Panexin Basic, Serum Replacement with Defined Components, GMP Grade. Composition Panexin basic contains purified proteins (< 1% w/v), lipids, salts, amino acids, trace elements, hormones and only traces of animal-derived components (< 1% w/v). It contains no growth factors, undefined hydrolysates or peptones. Advantages Panexin basic is designed to replace or to reduce serum in the cell culture in a very simple manner. In most cases there is no need to change the basal medium. As Panexin basic is fully defined and contains no peptones or hydrolysates, lot testing is no longer necessary. It also allows high reproducibility and a simplified downstream process. Panexin basic contains no growth factors and enables defined proliferation and differentiation of stem cells. Characterization studies of growth factors will obtain more reproducible and clearer results. Panexin basic is also useful to develop sensitive cell-based in vitro tests and co-culture procedures. Suitability Panexin basic is suitable for the cultivation of a variety of adherent and non-adherent cells under serumfree culture conditions or to reduce the necessary FBS amount in cell culture. (see Fig.1) Specifications Quality: Research Use Only (RUO) Cell Type: Various Culture Type: Adherent culture or suspension culture Liquid / Powder: Liquid Product Category: Serum Replacements Size: 50 ml, 100 ml, and 500 ml bottles Sterile: Yes Storage Temperature: -20°C, in the dark Manufacturer: PAN-Biotech GmbH Country of Origin: Germany Usage This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive. Other Names FBS replacement, FBS substitute, serum substitute Resources Product Datasheet (PDS) Material Safety Data Sheet (MSDS) Panexin Product References Product References Leonteva, Anastasia et al. “The Activity of Human NK Cells Towards 3D Heterotypic Cellular Tumor Model of Breast Cancer.” Cells vol. 14,14 1039. 8 Jul. 2025, doi:10.3390/cells14141039 Palmieri, Fabio et al. “One-Step Soft Agar Enrichment and Isolation of Human Lung Bacteria Inhibiting the Germination of Aspergillus fumigatus Conidia.” Microorganisms vol. 12,10 2025. 7 Oct. 2024, doi:10.3390/microorganisms12102025 Trefny, Marcel P et al. “Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.” Nature communications vol. 14,1 86. 2 Feb. 2023, doi:10.1038/s41467-022-35583-w Blaskovic, Sanja et al. “Di-Tyrosine Crosslinking and NOX4 Expression as Oxidative Pathological Markers in the Lungs of Patients with Idiopathic Pulmonary Fibrosis.” Antioxidants (Basel, Switzerland) vol. 10,11 1833. 18 Nov. 2021, doi:10.3390/antiox10111833 Wanes, Dalanda et al. “Proliferation and Differentiation of Intestinal Caco-2 Cells Are Maintained in Culture with Human Platelet Lysate Instead of Fetal Calf Serum.” Cells vol. 10,11 3038. 5 Nov. 2021, doi:10.3390/cells10113038 Related Products Panexin Basic, Serum Replacement with Defined Components, GMP Grade Panexin Serum Replacements Serum-Free Media Ilex Life Sciences LLC is an authorized distributor of PAN-Biotech GmbH.
