Description PAN-Biotech Panexin CD is a chemically defined, xeno-free serum replacement for the cultivation of adherent and non-adherent cells under serum-free culture conditions or to significantly reduce the amount of serum in cell culture. It supports the growth of many cell types in an optimum manner without any extra handling compared to serum. GMP Grade Panexin CD GMP is a ready-to-use, chemically defined serum replacement designed for direct use in GMP-regulated clinical and industrial applications. It enables serum-free cell culture or a significant reduction of serum while supporting the growth of both adherent and suspension cells. These features make Panexin CD GMP particularly suitable for clinical cell processing, cell and gene therapy, and biopharmaceutical development and manufacturing. The GMP grade version is based on the established Panexin CD formulation and is manufactured under strictly controlled GMP conditions. Its fully defined composition, high batch-to-batch consistency and comprehensive documentation make Panexin CD GMP a true ready-to-use solution that can be directly implemented in sensitive workflows without additional preparation steps. Applications Serum-free or serum-reduced cell culture under GMP conditions. Cultivation of adherent and non-adherent cells. Clinical cell processing and cell therapy. Cell and gene therapy workflows. Development of reproducible, chemically defined cell culture systems. Cell-based assays and co-culture models. Features Manufactured in compliance with Good Manufacturing Practice (GMP). Chemically defined serum replacement. Ready-to-use – immediately applicable. High batch-to-batch consistency and process reliability. Supports robust upstream and downstream processing. Composition Panexin CD is free of any animal or human-derived components. It contains recombinant proteins, lipids, salts, amino acids, trace elements, hormones and a 3-dimensional substrate release system in an optimized formulation. It contains no growth factors, undefined hydrolysates or peptones. Advantages Panexin CD is designed to replace or to reduce serum in the cell culture in a very simple manner. Compared to other serum replacements, it contains only chemically defined components. Due to its very defined character, lot testing is not necessary anymore. It also allows high reproducibility and simplified downstream processing. Panexin CD contains no growth factors and enables defined proliferation and differentiation of stem cells. Characterization studies of growth factors will obtain more reproducible and clearer results. Panexin CD is also useful to develop sensitive cell-based in vitro tests and coculture procedures. For cell lines which require specific growth factors these should be added in a concentration as previously used. Suitability Panexin CD is suitable for the cultivation of a variety of adherent and suspension cells under serum-free culture conditions or to reduce the necessary FBS amount in cell culture (see Fig.1). For instructions on cell adaptation from FBS, please refer to the Product Datasheet (PDS) and Application Note. Specifications Cat. No. CT-93100 Quality: GMP Grade (EU Annex 1) Cell Type: Various Culture Type: Adherent culture or suspension culture Liquid / Powder: Liquid Product Category: Serum Replacements Size: 100 ml Sterile: Yes Storage Temperature: -20°C, in the dark Manufacturer: PAN-Biotech GmbH Country of Origin: Germany Documents Material Safety Data Sheet (MSDS) PAN-Biotech GMP Product Factsheet Other Names GMP FBS replacement, GMP FBS substitute, GMP serum substitute Related Products RUO Version: Panexin CD, Serum Replacement with Chemically-Defined Components PAN-Biotech GMP Grade Cell Culture Products Panexin Serum Replacements Serum-Free Media Ilex Life Sciences LLC is an authorized distributor of PAN-Biotech GmbH.
