Neurturin is a cytokine with a molecular weight of 22 kDa, consisting of 195 amino acid residues. Along with GDNF, it belongs to the glial cell line-derived neurotrophic factor (GDNF) family. Neurturin binds to GFRα-2 (a GPI-anchored receptor known as GDNF family receptor alpha-2), thereby activating the Ret receptor tyrosine kinase and the MAPK signaling pathway. It plays a crucial role in neuronal survival. Specifications Cat.No. 92137ES08 / 92137ES20 / 92137ES60 / 92137ES76 Size 5 μg / 20 μg / 100 μg / 500 μg Components Name 92137ES08 92137ES20 92137ES60 92137ES76 HiActi™ Recombinant Mouse Neurturin Protein, His Tag 5 μg 20 μg 100 μg 500 μg Performance parameters Synonyms NTN, NRTN Species Mouse Expression Sequence PGARPCGLRELEVRVSELGLGYTSDETVLFRYCAGACEAAIRIYDLGLRRLRQRRRVRRERARAHPCCRPTAYEDEVSFLDVHSRYHTLQELSARECACV with polyhistidine tag at the N-terminus. Accession P97463 Tag N-His Expression System E.coli Molecular Weight The protein has a calculated MW of 12.33 kDa. The protein migrates as 11-17 kDa under reducing condition Purity >98% as determined by SDS-PAGE. Endotoxin