HiActi™ Recombinant Mouse IL-31 Protein, His Tag _ 90296ES

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Interleukin-31 (IL-31) is a cytokine with a molecular weight of 15.65 kDa, consisting of 141 amino acid residues. Primarily secreted by Th2 cells, IL-31 binds to a receptor known a s IL-31RA. Upon binding to IL-31RA, it activates multiple signaling pathways, including the MAPK, PI3K/AKT, and JAK/STAT pathways. It plays a crucial role in regulating various biological functions, such as cell proliferation, hematopoiesis, cytokine induction, inflammation, and immune responses. Additionally, it responds to antigens by promoting cell-mediated immunity. Specifications Cat.No. 90296ES08 / 90296ES20 / 90296ES60 / 90296ES76 Size 5 μg / 20 μg / 100 μg / 500 μg Components Name 90296ES08 90296ES20 90296ES60 90296ES76 HiActi™ Recombinant Mouse IL-31 Protein, His Tag 5 μg 20 μg 100 μg 500 μg Performance parameters Synonyms interleukin 31, IL31 Species Mouse Expression Sequence MSHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT with polyhistidine tag at the C-terminus. Accession Q6EBC2 Tag C-His Expression System E.coli Molecular Weight The protein has a calculated MW of 16.78 kDa. The protein migrates as 18 kDa under reducing condition Purity >98% as determined by SDS-PAGE. Endotoxin Show more